ArticleAnnals of surgical oncology2009
Ultrasound-guided laser-induced thermal therapy for small palpable invasive breast carcinomas: a feasibility study.
Article in Annals of surgical oncology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 83 citations in OpenAlex.
- Percutaneous Management of Breast Cancer: a Systematic Review.Current oncology reports · 2022Pooled it
- Technical success, technique efficacy and complications of minimally-invasive imaging-guided percutaneous ablation procedures of breast cancer: A systematic review and meta-analysis.European radiology · 2017Pooled it
- Incorporating Percutaneous Laser Ablation for Early Breast Cancer Treatment: A Systematic Review.Technology in cancer research & treatmentPooled it
- Landscape of the Peripheral Immune Response Induced by Local Microwave Ablation in Patients with Breast Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Trial
- Article
- Sentinel Lymph Node Biopsy in Melanoma: Overview and Updates.International journal of molecular sciences · 2025Review
- Comparison of local effects and systemic T-cell responses in patients with breast cancer treated by radiofrequency ablation versus microwave ablation.Cancer cell international · 2025Article
- In-situ, real-time monitoring of thermo-mechanical properties of biological tissues undergoing laser heating and ablation.Biomedical optics express · 2024Article
- The Role of Laser and Microwave in Treatment of Endocrine Disorders: A Systematic Review.Journal of lasers in medical sciences · 2024Review
- Cold air plasma improving rheumatoid arthritis via mitochondrial apoptosis pathway.Bioengineering & translational medicine · 2023Article
- Thermo-vibrational analyses of skin tissue subjected to laser heating source in thermal therapy.Scientific reports · 2021Article
- Endoscopic ultrasound (EUS)-guided cylindrical interstitial laser ablation (CILA) onBiomedical optics express · 2021Article
- Precision Breast-Conserving Surgery With Microwave Ablation Guidance: A Pilot Single-Center, Prospective Cohort Study.Frontiers in oncology · 2021Article
- Computational analysis of linear energy modulation for laser thermal coagulation.Biomedical optics express · 2018Article
- Article
- Defeating Cancers' Adaptive Defensive Strategies Using Thermal Therapies: Examining Cancer's Therapeutic Resistance, Ablative, and Computational Modeling Strategies as a means for Improving Therapeutic Outcome.Technology in cancer research & treatment · 2018Review
- Ablative techniques for the treatment of benign and malignant breast tumours.Journal of therapeutic ultrasound · 2017Review
- A review of ablative techniques in the treatment of breast fibroadenomata.Journal of therapeutic ultrasound · 2016Review
- Laser-induced interstitial thermotherapy via a single-needle delivery system: Optimal conditions of ablation, pathological and ultrasonic changes.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015Article
- Image-guided Percutaneous Ablation of Small Breast Cancer: Which Technique is Leading the Pack?Technology in cancer research & treatment · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe next step in breast-conserving surgery for small breast carcinomas could be local ablation. In this study, the feasibility of ultrasound-guided laser-induced thermal therapy (LITT) is evaluated.
methodsPatients with large-core needle biopsy-proven invasive, palpable breast carcinoma (clinically <or=2 cm) underwent ultrasound-guided LITT, followed by surgical excision. Completeness of ablation was determined by both hematoxylin and eosin staining and nicotinamide adenosine diaphorase staining.
resultsFourteen patients completed the treatment. The mean histological tumor size was 17 mm (range, 8-37 mm); 6 of 14 tumors were histologically larger than the clinical entry threshold of 2 cm. The power applied in all patients was 7 W, and the mean treatment time was 21.4 min (range, 15-30 min). In one patient, a skin burn occurred, and one patient had a localized pneumothorax that could be treated conservatively. In 7 (50%) of 14 patients, the tumor was completely ablated, as confirmed by nicotinamide adenosine diaphorase staining. In 11 cases, extensive in-situ carcinoma was present. In one case, the in-situ carcinoma was also completely ablated. A total of seven (88%) of eight tumors <2 cm in size were completely ablated versus one (17%) of six tumors that were >or=2 cm in size (P = .026).
conclusionsSuccessful LITT of invasive breast cancer seems to be feasible when confined to small (<2 cm) nonlobular carcinomas without surrounding extensive in-situ component and angioinvasion. However, to implement LITT in a curative setting, improvements in imaging to more reliably preoperatively assess tumor size and monitoring of fiber tip placement and treatment affect are essential.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.