ReviewCurrent opinion in neurology2009
Multisite neuroimaging trials.
Review in Current opinion in neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
57 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Study factors influencing ventricular enlargement in schizophrenia: a 20 year follow-up meta-analysis.NeuroImage · 2012Pooled it
- Early deprivation alters structural brain development from middle childhood to adolescence.Science advances · 2022Trial
- Multi-center reproducibility of structural, diffusion tensor, and resting state functional magnetic resonance imaging measures.Neuroradiology · 2018Trial
- Overcoming Site Variability in Multisite fMRI Studies: an Autoencoder Framework for Enhanced Generalizability of Machine Learning Models.Neuroinformatics · 2025Article
- Vendor-agnostic 3D multiparametric relaxometry improves cross-platform reproducibility.Magnetic resonance in medicine · 2025Article
- Automated quality control of T1-weighted brain MRI scans for clinical research datasets: methods comparison and design of a quality prediction classifier.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Kernel machine tests of association using extrinsic and intrinsic cluster evaluation metrics.PLoS computational biology · 2024Article
- Bayesian inference for group-level cortical surface image-on-scalar regression with Gaussian process priors.Biometrics · 2024Article
- The German research consortium for the study of bipolar disorder (BipoLife): a quality assurance protocol for MR neuroimaging data.International journal of bipolar disorders · 2024Article
- White matter tract alterations in schizophrenia identified by DTI-based probabilistic tractography: a multisite harmonisation study.Acta neuropsychiatrica · 2024Article
- Evidence for increased parallel information transmission in human brain networks compared to macaques and male mice.Nature communications · 2023Article
- Confounding Effects on the Performance of Machine Learning Analysis of Static Functional Connectivity Computed from rs-fMRI Multi-site Data.Neuroinformatics · 2023Article
- Removal of site effects and enhancement of signal using dual projection independent component analysis for pooling multi-site MRI data.The European journal of neuroscience · 2023Article
- Investigation of Neurofunctional Changes Over the Course of Electroconvulsive Therapy.The international journal of neuropsychopharmacology · 2023Article
- Functional connectivity with medial temporal regions differs across cultures during post-encoding rest.Cognitive, affective & behavioral neuroscience · 2022Article
- Bayesian Inference for Brain Activity from Functional Magnetic Resonance Imaging Collected at Two Spatial Resolutions.The annals of applied statistics · 2022Article
- Morphometric Integrated Classification Index: A Multisite Model-Based, Interpretable, Shareable and Evolvable Biomarker for Schizophrenia.Schizophrenia bulletin · 2022Article
- Three Dimensions of Association Link Migraine Symptoms and Functional Connectivity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Construction of a confounder-free clinical MRI dataset in the Mass General Brigham system for classification of Alzheimer's disease.Artificial intelligence in medicine · 2022Article
- The Atypical Effective Connectivity of Right Temporoparietal Junction in Autism Spectrum Disorder: A Multi-Site Study.Frontiers in neuroscience · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
purpose of reviewThe intent of this study is to review trends in multicenter neuroimaging trials and their value for research and implications for clinical treatment. RECENT
findingsThe rise in availability of MRI for detecting disorders in the living brain has made it an attractive technology for assessing neural structure and function in a number of prominent diseases. Geographic factors underlying diseased populations coupled with complementary neuroimaging research programs have led to an increase in multicenter neuroimaging trials and consortia. Neuroimaging has become a major focus for multiinstitutional research in progressive changes in brain architecture, proxy biomarkers of treatment response, and the effects of disease on patterns of cognitive activation and connectivity. Notable consortia and research trial studies have focused on Alzheimer's disease, pediatric brain cancer, and fetal alcohol syndrome, in addition to multiinstitutional collaborative programs for mapping the normal brain. Such large-scale efforts necessitate close coordination of image data collection protocols, ontology development, computational requirements, concerted data archiving, and sharing. SUMMARY: Multicenter neuroimaging trials, consortia, and collaboratives enable the acquisition of large-scale, purpose-driven datasets that can then be used by the broader community to model and predict clinical outcomes as well as guide clinicians in selecting treatment options for neurological disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.