Evidence map›Paper›PMID 19506280›Full record

ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2009

In-hospital case fatality rates for acute myocardial infarction in Romania.

Gabriel Tatu-Chitoiu, Mircea Cinteza, Maria Dorobantu, Mariana Udeanu, Olivia Manfrini, Carmine Pizzi, Marius Vintila, Dominic D Ionescu, Elvira Craiu, Daniel Burghina and 1 more

Abstract readMulticenter Study
In one paragraph

Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Acute Myocardial Infarction Mortality Rates and Trends in Romania between 1994 and 2017.International journal of environmental research and public health · 2019
    Article
  7. Association of major cardiovascular risk factors with the development of acute coronary syndrome in Lithuania.European heart journal supplements : journal of the European Society of Cardiology · 2014
    Article
  8. Observational
  9. Article
  10. Article
  11. Quality of acute coronary care in emerging economies.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2009
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Gabriel Tatu-ChitoiuFloreasca Emergency Hospital, Bucharest, Romania.
Mircea Cinteza
Maria Dorobantu
Mariana Udeanu
Olivia Manfrini
Carmine Pizzi
Marius Vintila
Dominic D Ionescu
Elvira Craiu
Daniel Burghina
Raffaele Bugiardini

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe the clinical characteristics, treatments and in-hospital case-fatality rates in an unselected population of patients admitted for acute myocardial infarction.

methodsFrom January 2000 to June 2007, we tracked consecutive patients who were admitted to 7 tertiary referral and 21 county hospitals in Romania for medical treatment of ST-segment elevation acute myocardial infarction. These patients were enrolled in the Romanian Registry for ST-segment Elevation Myocardial Infarction. For this prospective study, we collected data on demographic characteristics, cardiovascular risk factors, various aspects of treatment for myocardial infarction, and in-hospital death.

resultsThe 9186 patients in the study group had a mean age of 63.8 years. The median time from onset of symptoms to thrombolysis was 230 (interquartile range 120-510) minutes. Of the 9186 patients, 4986 (54.3%) had hypertension, 1974 (21.5%) had diabetes mellitus, 3545 (38.6%) had lipid disorders and 4653 (50.7%) were smokers. The in-hospital mortality rate was 12.7% (1170 deaths). The study group consisted of 2893 women and 6293 men. The women were older than the men and had higher rates of hypertension and diabetes mellitus but were less likely to be smokers. A smaller proportion of women than men presented within 2 hours after onset of symptoms (23.1% v. 34.4%, p < 0.001). Smaller proportions of women received thrombolytics (40.8% v. 53.5%, p < 0.001), anticoagulants (93.4% v. 95.2%; p = 0.001), antiplatelet agents (88.3% v. 91.2%, p < 0.001) and primary percutaneous coronary interventions (1.5% v. 2.2%, p = 0.030). The risk of in-hospital death was greater for women, even after adjustment for confounders (odds ratio 1.33, 95% confidence interval 1.13-1.56; p < 0.001).

interpretationThe rates of reperfusion therapy for patients with acute myocardial infarction were low, and in-hospital case-fatality rates were high in this study. Excess in-hospital mortality was more pronounced among women.

Indexed as

Hospital MortalityAgedAngioplasty, Balloon, CoronaryFemaleHumansMaleMiddle AgedMyocardial InfarctionPractice Patterns, Physicians'Prospective StudiesQuality of Health CareRegistriesRomaniaThrombolytic Therapy

Identifiers

PMID19506280
PMCPMC2691436

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.