ArticleNanomedicine (London, England)2009
Determining molecular mass distributions and compositions of functionalized dendrimer nanoparticles.
Article in Nanomedicine (London, England), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Topical strategies for antimicrobial delivery of peptide medicines for the management of chronic wounds.Discover nano · 2026Review
- Physical Properties of Nanoparticles That Result in Improved Cancer Targeting.Journal of oncology · 2020Review
- Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics.Theranostics · 2017Article
- Development and application of STEM for the biological sciences.Ultramicroscopy · 2012Review
- Development of Electron Energy Loss Spectroscopy in the Biological Sciences.MRS bulletin · 2012Article
- Nanoparticles: Dissected with electrons.Nature nanotechnology · 2010Article
- Imaging and quantifying the morphology of an organic-inorganic nanoparticle at the sub-nanometre level.Nature nanotechnology · 2010Article
- Imaging the distribution of individual platinum-based anticancer drug molecules attached to single-wall carbon nanotubes.Nanomedicine (London, England) · 2009Article
- Recent progress towards development of effective systemic chemotherapy for the treatment of malignant brain tumors.Journal of translational medicine · 2009Review
- Physiologic upper limit of pore size in the blood-tumor barrier of malignant solid tumors.Journal of translational medicine · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This study demonstrates that a combination of unconventional electron microscopy techniques provides a quantitative means of assessing the degree of monodispersity of gadolinium (Gd) diethylenetriamine pentaacetic acid-conjugated polyamidoamine (PAMAM) dendrimers, which are designed for diagnostic imaging and delivering chemotherapeutics. Specifically, analysis of images acquired in the scanning transmission electron microscopy mode yields the distribution of molecular weights of individual dendrimers, whereas analysis of images acquired in the energy-filtering transmission electron microscopy mode yields the distribution of Gd atoms bound to the dendrimer nanoparticles. Measured compositions of Gd-conjugated G7 and G8 PAMAM dendrimers were consistent with the known synthetic chemistry. The G7 dendrimers had a mass of 330 +/- 4 kDa and 266 +/- 4 Gd atoms (+/- standard error of the mean). The G8 dendrimers had a mass of 600 +/- 8 kDa and 350 +/- 5 Gd atoms (+/- standard error of the mean). This approach will be particularly attractive for assessing the mass, composition and homogeneity of metal-containing organic nanoparticles used in nanomedicine.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.