ArticleDevelopmental dynamics : an official publication of the American Association of Anatomists2009
Transcriptome analysis of the zebrafish pineal gland.
Article in Developmental dynamics : an official publication of the American Association of Anatomists, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 38 citations in OpenAlex.
- Identification of ordinal relations and alternative suborders within high-dimensional molecular data.Frontiers in bioinformatics · 2025Article
- Melanopsin elevates locomotor activity during the wake state of the diurnal zebrafish.EMBO reports · 2022Article
- Similarities of developmental gene expression changes in the brain between human and experimental animals: rhesus monkey, mouse, Zebrafish, and Drosophila.Molecular brain · 2021Article
- Unique transcriptional signatures of sleep loss across independently evolved cavefish populations.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2020Article
- Assessing phenotype order in molecular data.Scientific reports · 2019Article
- Agouti-Related Protein 2 Is a New Player in the Teleost Stress Response System.Current biology : CB · 2019Article
- Single Cell Sequencing of the Pineal Gland: The Next Chapter.Frontiers in endocrinology · 2019Review
- Characterization of basal gene expression trends over a diurnal cycle in Xiphophorus maculatus skin, brain and liver.Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2018Article
- Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish.Scientific reports · 2017Article
- The light-induced transcriptome of the zebrafish pineal gland reveals complex regulation of the circadian clockwork by light.Nucleic acids research · 2014Article
- Gene expression changes in aging zebrafish (Danio rerio) brains are sexually dimorphic.BMC neuroscience · 2014Article
- Functional development of the circadian clock in the zebrafish pineal gland.BioMed research international · 2014Review
- Habenular commissure formation in zebrafish is regulated by the pineal gland-specific gene unc119c.Developmental dynamics : an official publication of the American Association of Anatomists · 2013Article
- Systematic identification of rhythmic genes reveals camk1gb as a new element in the circadian clockwork.PLoS genetics · 2012Article
- Light and melatonin schedule neuronal differentiation in the habenular nuclei.Developmental biology · 2011Article
- Crx broadly modulates the pineal transcriptome.Journal of neurochemistry · 2011Article
- Dynamic analysis of BMP-responsive smad activity in live zebrafish embryos.Developmental dynamics : an official publication of the American Association of Anatomists · 2011Article
- Article
- Pineal-specific agouti protein regulates teleost background adaptation.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- RNA isolation method for single embryo transcriptome analysis in zebrafish.BMC research notes · 2010Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
The zebrafish pineal gland (epiphysis) is a site of melatonin production, contains photoreceptor cells, and functions as a circadian clock pace maker. Here, we have used microarray technology to study the zebrafish pineal transcriptome. Analysis of gene expression at three larval and two adult stages revealed a highly dynamic transcriptional profile, revealing many genes that are highly expressed in the zebrafish pineal gland. Statistical analysis of the data based on Gene Ontology annotation indicates that many transcription factors are highly expressed during larval stages, whereas genes dedicated to phototransduction are preferentially expressed in the adult. Furthermore, several genes were identified that exhibit day/night differences in expression. Among the multiple candidate genes suggested by these data, we note the identification of a tissue-specific form of the unc119 gene with a possible role in pineal development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.