ArticleEuropean radiology2009
Parametric exploration of the liver by magnetic resonance methods.
Article in European radiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Chinese tree shrews as a primate experimental animal eligible for the study of alcoholic liver disease: characterization and confirmation by MRI.Experimental animals · 2020Article
- Evaluation of liver fibrosis with a monoexponential model of intravoxel incoherent motion magnetic resonance imaging.Oncotarget · 2018Article
- The Clinical Implications of Fatty Pancreas: A Concise Review.Digestive diseases and sciences · 2017Review
- Protective Effect of Yang Mi Ryung® Extract on Noise-Induced Hearing Loss in Mice.Evidence-based complementary and alternative medicine : eCAM · 2017Article
- Pancreatic fat and β-cell function in overweight/obese children with nonalcoholic fatty liver disease.World journal of gastroenterology · 2015Article
- 3.0 T proton magnetic resonance spectroscopy of the liver: quantification of choline.World journal of gastroenterology · 2013Article
- Molecular MRI of liver fibrosis by a peptide-targeted contrast agent in an experimental mouse model.Investigative radiology · 2013Article
- Cross-sectional investigation of correlation between hepatic steatosis and IVIM perfusion on MR imaging.Magnetic resonance imaging · 2012Article
- MR Imaging of activated hepatic stellate cells in liver injured by CCl4 of rats with integrin-targeted ultrasmall superparamagnetic iron oxide.European radiology · 2011Article
- Assessment of relevant hepatic steatosis in obese adolescents by rapid fat-selective GRE imaging with spatial-spectral excitation: a quantitative comparison with spectroscopic findings.European radiology · 2011Article
- MRI-determined fat content of human liver, pancreas and kidney.World journal of gastroenterology · 2010Article
- Liver magnetic resonance imaging: State of the art.World journal of gastroenterology · 2010Article
- Perfusion magnetic resonance imaging of the liver.World journal of gastroenterology · 2010Review
- Liver fat content determined by magnetic resonance imaging and spectroscopy.World journal of gastroenterology · 2010Review
- Magnetic resonance spectroscopy to study hepatic metabolism in diffuse liver diseases, diabetes and cancer.World journal of gastroenterology · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MRI, as a completely noninvasive technique, can provide quantitative assessment of perfusion, diffusion, viscoelasticity and metabolism, yielding diverse information about liver function. Furthermore, pathological accumulations of iron and lipids can be quantified. Perfusion MRI with various contrast agents is commonly used for the detection and characterization of focal liver disease and the quantification of blood flow parameters. An extended new application is the evaluation of the therapeutic effect of antiangiogenic drugs on liver tumours. Novel, but already widespread, is a histologically validated relaxometry method using five gradient echo sequences for quantifying liver iron content elevation, a measure of inflammation, liver disease and cancer. Because of the high perfusion fraction in the liver, the apparent diffusion coefficients strongly depend on the gradient factors used in diffusion-weighted MRI. While complicating analysis, this offers the opportunity to study perfusion without contrast injection. Another novel method, MR elastography, has already been established as the only technique able to stage fibrosis or diagnose mild disease. Liver fat content is accurately determined with multivoxel MR spectroscopy (MRS) or by faster MRI methods that are, despite their widespread use, prone to systematic error. Focal liver disease characterisation will be of great benefit once multivoxel methods with fat suppression are implemented in proton MRS, in particular on high-field MR systems providing gains in signal-to-noise ratio and spectral resolution.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.