ArticleNeural plasticity2009
Visual deprivation decreases somatic GAD65 puncta number on layer 2/3 pyramidal neurons in mouse visual cortex.
Article in Neural plasticity, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Cortical Somatostatin Innervation Follows a Unique Experience-Independent Developmental Trajectory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Reciprocal interaction between cortical SST and PV interneurons in top-down regulation of retinothalamic refinement.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Implications of Extended Inhibitory Neuron Development.International journal of molecular sciences · 2021Review
- Endocannabinoid Signaling Contributes to Experience-Induced Increase of Synaptic Release Sites From Parvalbumin Interneurons in Mouse Visual Cortex.Frontiers in cellular neuroscience · 2020Article
- Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling.Neuropharmacology · 2018Article
- Integrating Hebbian and homeostatic plasticity: the current state of the field and future research directions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- Article
- Whisker Deprivation Drives Two Phases of Inhibitory Synapse Weakening in Layer 4 of Rat Somatosensory Cortex.PloS one · 2016Article
- Binocular pattern deprivation interferes with the expression of proteins involved in primary visual cortex maturation in the cat.Molecular brain · 2015Article
- Visual system plasticity in mammals: the story of monocular enucleation-induced vision loss.Frontiers in systems neuroscience · 2015Review
- Rebound potentiation of inhibition in juvenile visual cortex requires vision-induced BDNF expression.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Experience-dependent homeostatic synaptic plasticity in neocortex.Neuropharmacology · 2014Review
- GABAergic synapses: their plasticity and role in sensory cortex.Frontiers in cellular neuroscience · 2014Review
- GABA expression and regulation by sensory experience in the developing visual system.PloS one · 2012Article
- Effects of light deprivation on visual evoked potentials in migraine without aura.BMC neurology · 2011Article
- Loss of prestin does not alter the development of auditory cortical dendritic spines.Neural plasticity · 2011Article
- A refractory period for rejuvenating GABAergic synaptic transmission and ocular dominance plasticity with dark exposure.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- A specific requirement of Arc/Arg3.1 for visual experience-induced homeostatic synaptic plasticity in mouse primary visual cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Proper functioning of the visual system depends on maturation of both excitatory and inhibitory synapses within the visual cortex. Considering that perisomatic inhibition is one of the key factors that control the critical period in visual cortex, it is pertinent to understand its regulation by visual experience. To do this, we developed an immunohistochemical method that allows three-dimensional (3D) analysis of the glutamic acid decarboxylase (GAD) 65-positive inhibitory terminals in the visual cortex. Using this method on transgenic mice expressing yellow fluorescence protein (YFP) in a subset of neurons, we found that the number of somatic GAD65-puncta on individual layer 2/3 pyramidal neurons is reduced when mice are dark-reared from birth and reverted to normal levels by re-exposure to light. There was no change in GAD65-puncta volume or intensity. These results support the reorganization of inhibitory circuitry within layer 2/3 of visual cortex in response to changes in visual experience.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.