Evidence map›Paper›PMID 19503625›Full record

ArticleJournal of biomolecular techniques : JBT2009

Comparison of comparative genomic hybridization technologies across microarray platforms.

Susan D Hester, Laura Reid, Norma Nowak, Wendell D Jones, Joel S Parker, Kevin Knudtson, William Ward, Jay Tiesman, Nancy D Denslow

Open access · greenAbstract read
In one paragraph

Article in Journal of biomolecular techniques : JBT, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Susan D HesterCellular Toxicology Branch, National Health and Environmental Effects Laboratory, U.S. Environmental Protection Agency, 109 T.W. Alexander Drive, Research Triangle Park, NC 27711, USA. hester.susan@epa.gov
Laura Reid
Norma Nowak
Wendell D Jones
Joel S Parker
Kevin Knudtson
William Ward
Jay Tiesman
Nancy D Denslow
Environmental Protection Agency · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the 2007 Association of Biomolecular Resource Facilities Microarray Research Group project, we analyzed HL-60 DNA with five platforms: Agilent, Affymetrix 500K, Affymetrix U133 Plus 2.0, Illumina, and RPCI 19K BAC arrays. Copy number variation was analyzed using circular binary segmentation (CBS) analysis of log ratio scores from four independently assessed hybridizations of each platform. Data obtained from these platforms were assessed for reproducibility and the ability to detect formerly reported copy number variations in HL-60. In HL-60, all of the tested platforms detected genomic DNA amplification of the 8q24 locus, trisomy 18, and monosomy X; and deletions at loci 5q11.2~q31, 9p21.3~p22, 10p12~p15, 14q22~q31, and 17p12~p13.3. In the HL-60 genome, at least two of the five platforms detected five novel losses and five novel gains. This report provides guidance in the selection of platforms based on this wide-ranging evaluation of available CGH platforms.

Indexed as

Chromosome AberrationsAlgorithmsCase-Control StudiesChromosome DeletionChromosomes, Artificial, BacterialComparative Genomic HybridizationGene DosageGenetic VariationGenome, HumanHL-60 CellsHumansNucleic Acid Amplification TechniquesOligonucleotide Array Sequence AnalysisReference StandardsReproducibility of ResultsSoftwarearrayCGHBAC arrayHL-60

Identifiers

PMID19503625
PMCPMC2685605
OpenAlexW341882553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.