ArticleJournal of bacteriology2009
Biochemical evidence for a timing mechanism in prochlorococcus.
Article in Journal of bacteriology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 80 citations in OpenAlex.
- Time matters: circadian genetics and the molecular logic of human health and disease.Nature reviews. Genetics · 2026Review
- Time after time - circadian clocks through the lens of oscillator theory.FEBS letters · 2026Review
- Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational ModiBications under Light Disturbance.bioRxiv : the preprint server for biology · 2026Article
- Mutations in the circadian cycle drive adaptive plasticity in cyanobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Ecosystem relocation on Snowball Earth: Polar-alpine ancestry of the extant surface biosphere?Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Latitudinal diversity in circadian and light-sensing genes in an ecologically vital group of marine picoeukaryote algae.The ISME journal · 2025Article
- Two KaiABC systems control circadian oscillations in one cyanobacterium.Nature communications · 2024Article
- Diel Cycle Proteomics: Illuminating Molecular Dynamics in Purple Bacteria for Optimized Biotechnological Applications.International journal of molecular sciences · 2024Article
- Emergence of metabolic coupling to the heterotrophISME communications · 2024Article
- Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping.International journal of molecular sciences · 2023Review
- Article
- Microbial circadian clocks: host-microbe interplay in diel cycles.BMC microbiology · 2023Review
- From primordial clocks to circadian oscillators.Nature · 2023Article
- Damped Oscillating Phosphoryl Transfer Reaction in the Cyanobacterial Circadian Clock.ACS omega · 2023Article
- Snowball Earth, population bottleneck andProceedings. Biological sciences · 2021Article
- Critical Role of Light in the Growth and Activity of the Marine NFrontiers in microbiology · 2021Article
- The Circadian Clock-A Molecular Tool for Survival in Cyanobacteria.Life (Basel, Switzerland) · 2020Review
- Damped circadian oscillation in the absence of KaiA in Synechococcus.Nature communications · 2020Article
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7 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organisms coordinate biological activities into daily cycles using an internal circadian clock. The circadian oscillator proteins KaiA, KaiB, and KaiC are widely believed to underlie 24-h oscillations of gene expression in cyanobacteria. However, a group of very abundant cyanobacteria, namely, marine Prochlorococcus species, lost the third oscillator component, KaiA, during evolution. We demonstrate here that the remaining Kai proteins fulfill their known biochemical functions, although KaiC is hyperphosphorylated by default in this system. These data provide biochemical support for the observed evolutionary reduction of the clock locus in Prochlorococcus and are consistent with a model in which a mechanism that is less robust than the well-characterized KaiABC protein clock of Synechococcus is sufficient for biological timing in the very stable environment that Prochlorococcus inhabits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.