ArticleDevelopmental biology2009
Four distinct phases of basket/stellate cell migration after entering their final destination (the molecular layer) in the developing cerebellum.
Article in Developmental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 39 citations in OpenAlex.
- Increased understanding of complex neuronal circuits in the cerebellar cortex.Frontiers in cellular neuroscience · 2024Review
- Revisiting the development of cerebellar inhibitory interneurons in the light of single-cell genetic analyses.Histochemistry and cell biology · 2024Review
- Regulation of cerebellar network development by granule cells and their molecules.Frontiers in molecular neuroscience · 2023Review
- Dendritic Inhibition by Shh Signaling-Dependent Stellate Cell Pool Is Critical for Motor Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Morphological pseudotime ordering and fate mapping reveal diversification of cerebellar inhibitory interneurons.Nature communications · 2022Article
- Diverse Neuron Properties and Complex Network Dynamics in the Cerebellar Cortical Inhibitory Circuit.Frontiers in molecular neuroscience · 2019Article
- Moving into shape: cell migration during the development and histogenesis of the cerebellum.Histochemistry and cell biology · 2018Review
- Migration of Interneuron Precursors in the Nascent Cerebellar Cortex.Cerebellum (London, England) · 2018Article
- Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRα1 or RET Impairs Normal Cerebellar Motor Learning.Cell reports · 2017Article
- Postnatal Migration of Cerebellar Interneurons.Brain sciences · 2017Review
- Developmental delay in motor skill acquisition in Niemann-Pick C1 mice reveals abnormal cerebellar morphogenesis.Acta neuropathologica communications · 2016Article
- From migration to settlement: the pathways, migration modes and dynamics of neurons in the developing brain.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2016Review
- Molecular layer interneurons of the cerebellum: developmental and morphological aspects.Cerebellum (London, England) · 2015Review
- Electrophysiological and Immunohistochemical Evidence for an Increase in GABAergic Inputs and HCN Channels in Purkinje Cells that Survive Developmental Ethanol Exposure.Cerebellum (London, England) · 2015Article
- Heterogeneity and Bipotency of Astroglial-Like Cerebellar Progenitors along the Interneuron and Glial Lineages.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Developmental Coordination of Gene Expression between Synaptic Partners During GABAergic Circuit Assembly in Cerebellar Cortex.Frontiers in neural circuits · 2012Article
- Inhibition of cerebellar granule cell turning by alcohol.Neuroscience · 2010Article
- Occupy tissue: the movement in cancer metastasis.Cell adhesion & migrationReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
In the adult cerebellum, basket/stellate cells are scattered throughout the ML, but little is known about the process underlying the cell dispersion. To determine the allocation of stellate/basket cells within the ML, we examined their migration in the early postnatal mouse cerebellum. We found that after entering the ML, basket/stellate cells sequentially exhibit four distinct phases of migration. First, the cells migrated radially from the bottom to the top while exhibiting saltatory movement with a single leading process (Phase I). Second, the cells turned at the top and migrated tangentially in a rostro-caudal direction, with an occasional reversal of the direction of migration (Phase II). Third, the cells turned and migrated radially within the ML at a significantly reduced speed while repeatedly extending and withdrawing the leading processes (Phase III). Fourth, the cells turned at the middle and migrated tangentially at their slowest speed, while extending several dendrite-like processes after having completely withdrawn the leading process (Phase IV). Finally, the cells stopped and completed their migration. These results suggest that the dispersion of basket/stellate cells in the ML is controlled by the orchestrated activity of external guidance cues, cell-cell contact and intrinsic programs in a position- and time-dependent manner.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.