Evidence map›Paper›PMID 19500011›Full record

ArticleJournal of alternative and complementary medicine (New York, N.Y.)2009

Description of clinical risk factor changes during naturopathic care for type 2 diabetes.

Ryan Bradley, Eva Kozura, Heather Buckle, Jennifer Kaltunas, Setareh Tais, Leanna J Standish

Abstract read
In one paragraph

Article in Journal of alternative and complementary medicine (New York, N.Y.), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 4 pooled it
10.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Intermittent fasting for the prevention of cardiovascular disease.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013
    Trial
  6. Trial
  7. Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers.Journal of alternative and complementary medicine (New York, N.Y.) · 2011
    Trial
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. The State of the Evidence for Whole-System, Multi-Modality Naturopathic Medicine: A Systematic Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019
    Article
  16. Can naturopathy provide answers to the escalating health care costs in India?Journal of traditional and complementary medicine · 2015
    Review
  17. Article
  18. CAM: naturopathic dietary interventions for patients with type 2 diabetes.Complementary therapies in clinical practice · 2011
    Article
  19. Observed Changes in Risk during Naturopathic Treatment of Hypertension.Evidence-based complementary and alternative medicine : eCAM · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryan BradleyBastyr University Research Center, 14500 Juanita Dr NE, Kenmore, WA 98028, USA. rbradley@bastyr.edu
Eva Kozura
Heather Buckle
Jennifer Kaltunas
Setareh Tais
Leanna J Standish
Bastyr University · USInstitute of Translational Health Sciences · US

Funding

Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
Institute for Translational Health Science (KL2)KL2RR025015 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$9.3M
Training in Complementary and Alternative Medical ResearchT32AT000815 · NCCIH · BASTYR UNIVERSITY · PI STANDISH, LEANNA J · 2002 to 2011
$3.2M
NCATS NIH HHS UL1 TR000423NCCIH NIH HHS 5T32 AT00815-03NCRR NIH HHS 1KL2RR025015-01NCRR NIH HHS KL2 RR025015
6 · The paper itself

Abstract

backgroundSurvey findings report that 48% of people with type 2 diabetes use complementary and alternative medicine (CAM) practice. Publications suggest a high incidence of health promotion counseling in naturopathic practice, yet clinical data on risk factor changes are not available in the literature.

objectivesThe primary aim of this study was to describe clinical risk factor changes during the utilization of naturopathic CAM services in patients with type 2 diabetes.

designA retrospective, observational study design was used to describe naturopathic care.

settingAbstracted medical charts were from patients of the Bastyr Center for Natural Health in Seattle, WA.

participantsThe patients in this study had type 2 diabetes and received naturopathic care between 2001 and 2006. OUTCOMES: Abstracted data included patient demographics, duration of care, number of visits, laboratory values for hemoglobin A1c (HbA1c), low density lipoprotein (LDL) and high density lipoprotein (HDL) cholesterol, triglycerides (TAG); and systolic/diastolic blood pressure (SPB, DBP).

resultsThirty-seven (37) patient records met inclusion criteria and were abstracted in detail. Mean and median duration of care were 27 and 20 months, respectively. The mean number of visits was 11. Significant mean changes in clinical laboratory risk factors over the duration of care were: -0.65% for HbA1c (p = 0.046), -45 mg/dL for TAG (p = 0.037), -7 mm Hg in SBP (p = 0.02), and -5 mm Hg in DBP (p = 0.003). Mean changes for cholesterol did not reach statistical significance. The percentage of patients who reached new control, had clinically significant risk factor improvements, or had any improvement was: 26%, 42%, and 68% for HbA1c, 7%, 28%, and 62% for LDL, 0%, 25%, and 39% for HDL, 14%, 38%, and 52% for TAG, 16%, 51%, and 86% for SBP, and 27%, 54%, and 70% for DBP. COMMENTS/

conclusionsThese preliminary outcomes suggest that risk factor improvements occur during naturopathic care for diabetes, although the contribution of naturopathic care to these changes cannot be determined. Effectiveness and generalizability of naturopathic approaches in treating type 2 diabetes should be evaluated in controlled prospective studies in representative populations or randomized trials.

Indexed as

NaturopathyBlood PressureCholesterolDiabetes Mellitus, Type 2FemaleGlycated HemoglobinHealth PromotionHumansMaleMiddle AgedOutpatient Clinics, HospitalRetrospective StudiesRisk FactorsTreatment OutcomeTriglyceridesCholesterolGlycated Hemoglobinhemoglobin A1c protein, humanTriglycerides

Identifiers

PMID19500011
PMCPMC3046878
OpenAlexW2037624022

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.