ReviewThe journal of headache and pain2009
Migraine pain: reflections against vasodilatation.
Review in The journal of headache and pain, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Diagnostic value of combined detection of serum NLR and CRP for migraine patients in the attack stage: A prospective study.Journal of medical biochemistry · 2026Article
- Fremanezumab for the treatment of migraine.Pain management · 2025Review
- Evaluation of Systemic Renin and Angiotensin II Levels in Normal Tension Glaucoma.Journal of clinical medicine · 2020Article
- Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines.PloS one · 2018Article
- Changes in retinal vessel diameters in migraine patients during attack-free period.International journal of ophthalmology · 2017Article
- Meningeal blood flow is controlled by H2 S-NO crosstalk activating a HNO-TRPA1-CGRP signalling pathway.British journal of pharmacology · 2016Article
- Evaluation of choroidal thickness using spectral-domain optical coherence tomography in migraine patients during acute migraine attacks: a comparative study.Eye (London, England) · 2014Article
- Migraine in gulf war illness and chronic fatigue syndrome: prevalence, potential mechanisms, and evaluation.Frontiers in physiology · 2013Article
- A PEPTIDE UNCOUPLING CRMP-2 FROM THE PRESYNAPTIC Ca(2+) CHANNEL COMPLEX DEMONSTRATES EFFICACY IN ANIMAL MODELS OF MIGRAINE AND AIDS THERAPY-INDUCED NEUROPATHY.Translational neuroscience · 2012Article
- Alcohol and migraine: what should we tell patients?Current pain and headache reports · 2011Review
- Migraine is a neuronal disease.Journal of neural transmission (Vienna, Austria : 1996) · 2011Review
- Headache associated with moyamoya disease: a case story and literature review.The journal of headache and pain · 2010Review
- Advances in CGRP Monoclonal Antibodies as Migraine Therapy: A Narrative Review.Saudi journal of medicine & medical sciencesArticle
- Alcohol-induced headaches: Evidence for a central mechanism?Journal of neurosciences in rural practiceReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The original Wolff's vascular theory of migraine was supported by the discovery of a class of drugs, the triptans, developed as a selective cephalic vasoconstrictor agents. Even in the neurovascular hypothesis of Moskowitz, that is the neurogenic inflammation of meningeal vessels provoked by peptides released from trigeminal sensory neurons, the vasodilatation provoked by calcitonin gene-related peptide (CGRP) is considered today much more important than oedema. The role of cephalic vasodilatation as a cause of migraine pain was recently sustained by studies showing the therapeutic effect of CGRP receptor antagonists. We discuss the evidence against vasodilatation as migraine pain generator and some findings which we suggest in support of a central (brain) origin of pain.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.