Evidence map›Paper›PMID 19498432›Full record

ArticleNature reviews. Neurology2009

Neurodegenerative disease: Diabetes, microvascular pathology and Alzheimer disease.

Raj N Kalaria

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature reviews. Neurology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Diabetic Kinome Inhibitors-A New Opportunity for β-Cells Restoration.International journal of molecular sciences · 2021
    Review
  8. Article
  9. Article
  10. Interaction betweenAlzheimer's & dementia (Amsterdam, Netherlands) · 2020
    Article
  11. Article
  12. Article
  13. Review
  14. Quantitative quality-control metrics forBiomedical optics express · 2019
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Raj N KalariaInstitute for Ageing and Health, Wolfson Research Center (Neuropathology),Newcastle General Hospital, Westgate Road,Newcastle upon Tyne, UK. r.n.kalaria@ncl.ac.uk

Funding

Medical Research Council G0400074Medical Research Council G0500247Medical Research Council G0502157
6 · The paper itself

Abstract

Epidemiological studies suggest that the risk of developing cognitive impairment and dementia is increased in individuals with diabetes mellitus, although the evidence from clinicopathological studies on neurodegenerative changes is at odds with these observations. A thorough appraisal of concomitant vascular changes in dementia might resolve this incongruity.

Indexed as

Alzheimer DiseaseAmyloid beta-PeptidesCardiovascular DiseasesCognition DisordersDiabetes MellitusHumansMicrovesselsNeurodegenerative DiseasesRisk FactorsAmyloid beta-Peptides

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.