Evidence map›Paper›PMID 19497721›Full record

ReviewCurrent opinion in immunology2009

Human B cell memory.

Antonio Lanzavecchia, Federica Sallusto

Open access · bronzeAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 86 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Humoral immunity in cancer.Signal transduction and targeted therapy · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Nanobodies-Useful Tools for Allergy Treatment?Frontiers in immunology · 2020
    Review
  12. Article
  13. Post-treatment human papillomavirus antibody kinetics in cervical cancer patients.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019
    Article
  14. Review
  15. [Therapy-resistant cells of the B cell line].Zeitschrift fur Rheumatologie · 2016
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Antonio LanzavecchiaInstitute for Research in Biomedicine, Bellinzona, Switzerland. lanzavecchia@irb.unisi.ch
Federica Sallusto

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following an immune response two types of differentiated B cells persist in the memory pool: plasma cells, which confer immediate protection by the secretion of specific antibodies; and memory B cells, which confer rapid and enhanced response to secondary challenge. We will review recent advances in understanding the heterogeneity, dynamics, and persistence of human memory B cells and plasma cells as well as new methods to isolate human monoclonal antibodies. These findings offer new insights into the human B cell response, which are relevant for vaccination and therapeutic intervention.

Indexed as

Antibodies, MonoclonalB-LymphocytesHumansImmunologic MemoryPlasma CellsVaccinationVirus DiseasesAntibodies, Monoclonal

Identifiers

PMID19497721
PMCPMC7134627
OpenAlexW2023778746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.