Evidence map›Paper›PMID 19497643›Full record

Trial reportAtencion primaria2009

[Non-pharmacological intervention as a strategy to improve antihypertensive treatment compliance].

Emilio Márquez Contreras, Nieves Martel Claros, Vicente Gil Guillén, José Luis Martín De Pablos, Mariano De la Figuera Von Wichman, José Joaquín Casado Martínez, Jacinto Espinosa García, José Carlos Pastoriza Vilas

Open access · greenAbstract readEnglish AbstractMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Atencion primaria, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 5 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 5 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. [In Process Citation].Atencion primaria · 2015
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Emilio Márquez ContrerasCentro de Salud la Orden, Huelva, España. Electronic address: emarquezc@papps.org.
Nieves Martel ClarosUnidad de Hipertensión, Hospital Clínico San Carlos, Madrid, España.
Vicente Gil GuillénCentro de Salud Monovar, Alicante, España.
José Luis Martín De PablosCentro de Salud la Orden, Huelva, España.
Mariano De la Figuera Von WichmanABS la Mina, Barcelona, España.
José Joaquín Casado MartínezCentro de Salud la Orden, Huelva, España.
Jacinto Espinosa GarcíaCentro de Salud Villanueva de la Serena, Villanueva de la Serena, Badajoz, España.
José Carlos Pastoriza VilasCentro de Salud Adoratrices, Huelva, España.
Centro de Salud Casa del Barco · ESHospital Clínico San Carlos · ESUniversidad de Huelva · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the efficacy of an intervention by means of an educational magazine on treatment compliance in uncontrolled arterial hypertension (AHT).

designControlled, randomised clinical trial.

setting87 primary care centres. Spain.

participantsA total of 450 patients with uncontrolled hypertension were included.

interventionTwo groups of 225 patients were formed: 1) Control group (CG): standard health intervention; 2) Intervention Group (IG): received a twice monthly educational magazine at home. MAIN MEASUREMENTS: Compliance was measured using the Medication Event Monitoring System (MEMS-Aardex). Compliance rate (CR) was recorded. Compliers were defined as individuals with a treatment compliance of 80-110%. The percentage of compliers, the mean percentage of doses taken and the percentage of patients taking the medication at the correct times were estimated. The mean blood pressures (BPs) and the percentage of controlled patientswere calculated. The number needed to treat (NNT) was calculated.

resultsA total of 393 individuals were evaluable (Age: 62.4 years), 196 in the IG and 197 in the CG. There were 83.2% (95% CI 78-88.4) and 49.2% (95% CI 42.2-56.2) (P=0.0001) of overall compliers in the IG and CG, respectively and 74% (95% CI: 67.9-80.1) and 42.6% (95% CI=35.7-49.5) (P=0.0001) of correct times compliers. A total of 81.6% (95% CI=76.2-86.5%)) were controlled in the IG and 56.3% (95% CI=49.4-63.2) in the CG. The NNT was 3.3 patients.

conclusionsTherapeutic non-compliance was very high. The educational magazine is an effective strategy to improve the compliance and degree of control of the AHT.

Indexed as

Medication AdherencePatient Education as TopicFemaleHumansHypertensionMaleMiddle Aged

Identifiers

PMID19497643
PMCPMC7022104
OpenAlexW2158717000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.