ReviewThe journal of headache and pain2009
Focus on headache as an adverse reaction to drugs.
Review in The journal of headache and pain, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 29 citations in OpenAlex.
- Pharmacokinetics and Safety of the Nucleoside Analog Antiviral Drug Galidesivir Administered to Healthy Adult Subjects.Clinical pharmacology in drug development · 2022Trial
- Multiple Drug Intolerance Syndrome and Arterial Hypertension-Systematic Review and Meta-Analysis.Journal of clinical medicine · 2025Review
- Article
- Imaging in headache disorders.Australian prescriber · 2022Review
- Frequency and Duration of Early Non-serious Adverse Events in Patients with Rheumatoid Arthritis and Psoriatic Arthritis Treated with Tofacitinib.Rheumatology and therapy · 2022Article
- Headache as an Adverse Reaction to the Use of Medication in the Elderly: A Pharmacovigilance Study.International journal of environmental research and public health · 2021Article
- Polypharmacy Among Headache Patients: A Cross-Sectional Study.CNS drugs · 2018Observational
- Cluster-like headache attacks triggered by nitrofurantoin intake.European journal of clinical pharmacology · 2014Article
- Article
- A review of methods used in assessing non-serious adverse drug events in observational studies among type 2 diabetes mellitus patients.Health and quality of life outcomes · 2011Review
- Future drugs for migraine.Internal and emergency medicine · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There are a large number of drugs inducing headache as an adverse reaction. Nevertheless, headaches as adverse reactions to drugs have received limited attention. Non-serious adverse reactions, such as headache, are not quantified and described as accurately as serious, life threatening ones. However, non-serious reactions can also be extremely troublesome, above all when they are chronic: they can affect patients' quality of life and contribute to non-compliance. It is absolutely possible that the number of patients with headache as an adverse reaction, which is going to increase, considering the growing use of medications. Physicians should, therefore, be aware of this issue. Indeed, it is difficult to attribute the diagnosis of adverse drug reaction to a condition, headache, which is also a very common symptom in general population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.