Evidence map›Paper›PMID 19494079›Full record

ArticleJournal of clinical microbiology2009

Polyomavirus shedding in the stool of healthy adults.

John A Vanchiere, Suhaib Abudayyeh, Christina M Copeland, Lee B Lu, David Y Graham, Janet S Butel

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Shotgun metagenomics on indoor air for surveillance of respiratory, enteric, and skin viruses in a Belgian daycare setting, January to December 2022.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025
    Article
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  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Smoking is not associated with higher prevalence of JC virus in MS patients.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Fecal Polyomavirus Excretion in Infancy.Journal of the Pediatric Infectious Diseases Society · 2016
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

John A VanchiereDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA. jvanch@lsuhsc.edu
Suhaib Abudayyeh
Christina M Copeland
Lee B Lu
David Y Graham
Janet S Butel
Baylor College of Medicine · USLouisiana State University Health Sciences Center Shreveport · USOffice of Infectious Diseases · US

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
SV40 Pathogenesis of Human InfectionsR01CA104818 · NCI · BAYLOR COLLEGE OF MEDICINE · PI BUTEL, JANET S · 2004 to 2008
$2.4M
The Role of Polyomaviruses in Pediatric Renal DiseasesK08DK062090 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI VANCHIERE, JOHN ANTHONY · 2002 to 2006
$603k
NCI NIH HHS CA104818NCI NIH HHS R01 CA104818NIDDK NIH HHS DK56338NIDDK NIH HHS DK62090NIDDK NIH HHS K08 DK062090NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

We recently reported the frequent detection of polyomaviruses (BK virus [BKV] or simian virus 40 [SV40]) in 46% of stool samples from hospitalized children. In order to determine if adults exhibit fecal shedding of polyomavirus, single stool specimens from healthy adults were evaluated by PCR. Overall, 20 (18.2%) of 110 specimens were positive for human polyomaviruses: 9 with BKV, 9 with JC virus (JCV), 1 with SV40, and 1 with both JCV and SV40. Among the 94 subjects without immune compromise, 17 (18.1%) were excreting polyomaviruses. This shedding frequency in adults was significantly lower than that observed in children (P < 0.001). These findings support the hypothesis that the gastrointestinal tract may be a site of polyomavirus persistence, and they suggest a fecal-oral route of viral transmission.

Indexed as

Virus SheddingAdultAgedAged, 80 and overCarrier StateDNA, ViralFecesFemaleHumansMaleMiddle AgedPolymerase Chain ReactionPolyomavirusPolyomavirus InfectionsPrevalenceYoung AdultDNA, Viral

Identifiers

PMID19494079
PMCPMC2725650
OpenAlexW2022460206

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.