Assessing human immunodeficiency virus type 1 tropism: Comparison of assays using replication-competent virus versus plasma-derived pseudotyped virions.
Noriaki Hosoya, Zhaohui Su, Timothy Wilkin, Roy M Gulick, Charles Flexner, Michael D Hughes, Paul R Skolnik, Françoise Giguel, Wayne L Greaves, Eoin Coakley and 1 more
Article in Journal of clinical microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors.
Noriaki HosoyaBrigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Zhaohui Su
Timothy Wilkin
Roy M Gulick
Charles Flexner
Michael D Hughes
Paul R Skolnik
Françoise Giguel
Wayne L Greaves
Eoin Coakley
Daniel R Kuritzkes
Funding
Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI Daniel Lingwood · 2004 to 2026
$94.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024996 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2007 to 2011
$49.6M
Weill Cornell Medicine - Rutgers New Jersey Medical School Clinical Trials UnitUM1AI069419 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ROY M. GULICK · 2012 to 2026
$44.6M
Partners Healthcare Systems/Harvard Medical School/Boston Medical Center AIDS CTUU01AI069472 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI KURITZKES, DANIEL R. · 2007 to 2011
$15.4M
Cornell Clinical Trials UnitU01AI069419 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI GULICK, ROY M. · 2007 to 2011
$6.5M
Partners Healthcare Systems/Harvard Medical School/Boston Medical Center AIDS CTUUM1AI069472 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI KURITZKES, DANIEL R. · 2012 to 2014
$6.0M
HIV-1 Resistance to Chemokine Receptor AntagonistsR37AI055357 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI KURITZKES, DANIEL R. · 2007 to 2016
$4.4M
Antiretroviral Therapy for HIV-Infected PatientsK24AI051966 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI GULICK, ROY M. · 2003 to 2012
$1.6M
Fitness of Enfuvirtide-(T-20)-Resistant HIV-1R01AI055357 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI KURITZKES, DANIEL R · 2003 to 2006
$1.2M
HIV-1 THERAPEUTICS AND DRUG RESISTANCEK24RR016482 · NCRR · UNIVERSITY OF COLORADO DENVER · PI KURITZKES, DANIEL R. · 2001 to 2010
Detection of CXCR4-using human immunodeficiency virus by the Trofile assay was compared to that by assays using virus isolates or replication-competent recombinants. Concordance with the Trofile assay was good, but assays using replicating viruses did not increase substantially the ability to detect the presence of CXCR4-using virus.
Indexed as
Virus InternalizationVirus ReplicationHIV-1HumansPlasmaReceptors, VirusSensitivity and SpecificityVirologyReceptors, Virus
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Assessing human immunodeficiency virus type 1 tropism: Comparison of assays using replication-competent virus versus plasma-derived pseudotyped virions. · full record | OpenQuestion