Evidence map›Paper›PMID 19492966›Full record

ReviewFuture microbiology2009

Clinical and laboratory evidence for Neisseria meningitidis biofilms.

R Brock Neil, Michael A Apicella

Abstract readReview
In one paragraph

Review in Future microbiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. The role of extracellular DNA inJournal of bacteriology · 2026
    Review
  2. Review
  3. A Rare Mutation in SPLUNC1 Affects Bacterial Adherence and Invasion in Meningococcal Disease.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Biofilm formation by the human pathogen Neisseria meningitidis.Medical microbiology and immunology · 2010
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

R Brock NeilUniversity of Iowa, Hygienic Laboratory, 102 Oakdale Campus, H101 OH, Iowa City, IA 52242-5002, USA.
Michael A Apicella

Funding

THE BIOLOGY OF PATHOGENIC NEISSERIAR01AI045728 · NIAID · UNIVERSITY OF IOWA · PI APICELLA, MICHAEL A. · 1999 to 2010
$3.7M
NIAID NIH HHS AI AI045728NIAID NIH HHS R01 AI045728
6 · The paper itself

Abstract

Neisseria meningitidis is the etiologic agent of meningococcal meningitis. Carriage of the organism is approximately 10% while active disease occurs at a rate of 1:100,000. Recent publications demonstrate that N. meningitidis has the ability to form biofilms on glass, plastic or cultured human bronchial epithelial cells. Microcolony-like structures are also observed in histological sections from patients with active meningococcal disease. This review investigates the possible role of meningococcal biofilms in carriage and active disease, based on the laboratory and clinical aspects of the disease.

Indexed as

BiofilmsCarrier StateHumansMeningococcal InfectionsNeisseria meningitidis

Identifiers

PMID19492966
PMCPMC2827931

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.