ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2009
The motile cilium in development and disease: emerging new insights.
Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
26 citing papers in PubMed, 42 citations in OpenAlex.
- Two-directional trafficking of the IFT25 protein in the developing mouse sperm flagella.Biology of reproduction · 2025Article
- Down-expression of Foxj1 on airway epithelium with impaired cilia architecture in non-cystic fibrosis bronchiectasis implies disease severity.The clinical respiratory journal · 2023Article
- IFT54 directly interacts with kinesin-II and IFT dynein to regulate anterograde intraflagellar transport.The EMBO journal · 2021Article
- Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress.The EMBO journal · 2018Article
- Developmental expression of the zebrafish Arf-like small GTPase paralogs arl13a and arl13b.Gene expression patterns : GEP · 2018Article
- Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes.Nature neuroscience · 2017Article
- Transcriptional regulation of human sperm-associated antigen 16 gene by S-SOX5.BMC molecular biology · 2017Article
- Fine-Tuning Motile Cilia and Flagella: Evolution of the Dynein Motor Proteins from Plants to Humans at High Resolution.Molecular biology and evolution · 2016Article
- Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease.PLoS genetics · 2016Article
- PIERCE1 is critical for specification of left-right asymmetry in mice.Scientific reports · 2016Article
- Article
- RFX7 is required for the formation of cilia in the neural tube.Mechanisms of development · 2014Article
- Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm.Journal of medical genetics · 2014Article
- The roles of evolutionarily conserved functional modules in cilia-related trafficking.Nature cell biology · 2013Review
- The Chlamydomonas mutant pf27 reveals novel features of ciliary radial spoke assembly.Cytoskeleton (Hoboken, N.J.) · 2013Article
- Birt-Hogg-Dube syndrome is a novel ciliopathy.Human molecular genetics · 2013Article
- The MIA complex is a conserved and novel dynein regulator essential for normal ciliary motility.The Journal of cell biology · 2013Article
- Photoreceptor sensory cilia and ciliopathies: focus on CEP290, RPGR and their interacting proteins.Cilia · 2012Article
- Article
- Both sequence and context are important for flagellar targeting of a glucose transporter.Journal of cell science · 2012Article
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this paper, I review a collection of recently published papers that have provided significant new information about the biogenesis and functions of motile cilia. In vertebrates, the activity of motile cilia has been associated with a fascinating diversity of developmental and physiological processes. Despite the importance, much remains to be learned about the genetic control and cellular events that are involved in the differentiation of motile cilia. We also need to better understand the mechanisms by which cilia-driven fluid flow is able to influence such a variety of developmental and physiological processes. The Foxj1 family of proteins has now been definitively established as master regulators of motile ciliogenesis.1,2 Identification of the Kintoun/PF13 protein has shed light on the assembly of dynein arms,3 whereas live imaging of ciliary motility has led to the discovery of an intriguing new role for motile cilia in otolith formation in the ear.4.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.