ReviewNature reviews. Rheumatology2009
Surgical options for patients with osteoarthritis of the knee.
Review in Nature reviews. Rheumatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Effects of aquatic exercise on pain and physical function in overweight/obese patients with lower limb osteoarthritis: a systematic review and meta-analysis.Frontiers in physiology · 2026Pooled it
- Core Recommendations for Osteoarthritis Care: A Systematic Review of Clinical Practice Guidelines.Arthritis care & research · 2023Pooled it
- Comparative study of high tibial osteotomy using dynamic axial fixator and locked low-profile plate in medial osteoarthritis of knee.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2015Trial
- CT-based 3D bone shape modes are associated with clinically meaningful functional improvement after total knee arthroplasty.Osteoarthritis and cartilage open · 2026Article
- Forecasting knee arthroplasty surgery with deep learning : an integrated approach using routine clinical data and radiographs.Bone & joint open · 2026Article
- Article
- Immunomodulatory biomaterials for osteoarthritis: Targeting inflammation and enhancing cartilage regeneration.Materials today. Bio · 2025Review
- The association between surgeon grade and radiographic implant alignment following oxford unicompartmental knee replacement.Archives of orthopaedic and trauma surgery · 2025Article
- 9. Chronic knee pain.Pain practice : the official journal of World Institute of Pain · 2025Review
- Surgical interventions in Severe Osteoarthritis: Pros and Cons.Journal of orthopaedics and sports medicine · 2025Article
- High return to sport rate in patients undergoing image-based robotic arm assisted unicompartmental knee arthroplasty.Archives of orthopaedic and trauma surgery · 2024Article
- Clinical and functional outcomes of TKA after HTO or UKA: a New Zealand Joint Registry Study.Archives of orthopaedic and trauma surgery · 2024Article
- Advancing Tissue Damage Repair in Geriatric Diseases: Prospects of Combining Stem Cell-Derived Exosomes with Hydrogels.International journal of nanomedicine · 2024Review
- FUNCTIONAL CAPACITY IN PATIENTS WITH KNEE OSTEOARTHRITIS: CROSS-SECTIONAL STUDY.Acta ortopedica brasileira · 2024Article
- Comparison of Femoral Component Rotation between Robotic-Assisted vs. Soft-Tissue Tensor Total Knee Arthroplasty with Anatomic Implants.Medicina (Kaunas, Lithuania) · 2023Article
- Bibliometric Analysis of Publications in Clinical Trials on Knee Osteoarthritis Between 2001 and 2022.Journal of pain research · 2023Article
- Targeted and responsive biomaterials in osteoarthritis.Theranostics · 2023Review
- Paroxetine Attenuates Chondrocyte Pyroptosis and Inhibits Osteoclast Formation by Inhibiting NF-κB Pathway Activation to Delay Osteoarthritis Progression.Drug design, development and therapy · 2023Article
- Engineering Hyaluronic Acid for the Development of New Treatment Strategies for Osteoarthritis.International journal of molecular sciences · 2022Review
- Awareness about total knee replacement among Saudi population.Journal of family medicine and primary care · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) of the knee is a progressive disease that ultimately damages the entire joint. Knee OA should initially be treated conservatively, but surgery should be considered if symptoms persist. Surgical treatments for knee OA include arthroscopy, osteotomy and knee arthroplasty; determining which of these procedures is most appropriate will depend on several factors, including the location and severity of OA damage, patient characteristics and risk factors. Arthroscopic lavage and debridement do not alter disease progression, and should not be used as a routine treatment for the osteoarthritic knee. Bone marrow stimulation techniques such as microfracture are primarily used to treat focal chondral defects; the evidence for the use of these techniques for knee OA remains unclear. The goal of osteotomy for unicompartmental knee OA is to transfer the weight load from the damaged compartment to undamaged areas, delaying the need for joint replacement. This procedure should be considered in young and active patients who are not suitable candidates for knee arthroplasty. For patients with severe OA, total knee arthroplasty can be a safe, rewarding and cost-effective treatment. In selected patients with isolated medial or patellofemoral OA, unicompartmental knee arthroplasty and patellofemoral replacement, respectively, can be successful.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.