Evidence map›Paper›PMID 19491703›Full record

ArticleJournal of hypertension2009

Preventing misdiagnosis of ambulatory hypertension: algorithm using office and home blood pressures.

Daichi Shimbo, Sujith Kuruvilla, Donald Haas, Thomas G Pickering, Joseph E Schwartz, William Gerin

Open access · greenAbstract read
In one paragraph

Article in Journal of hypertension, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Observational
  6. Observational
  7. Algorithm for diagnosing hypertension using out-of-office blood pressure measurements.Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
  8. Article
  9. Evaluation of Criteria to Detect Masked Hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2016
    Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Daichi ShimboCenter for Behavioral Cardiovascular Health, Department of Medicine, Columbia University Medical Center, New York, NY 10032, USA. ds2231@columbia.edu
Sujith Kuruvilla
Donald Haas
Thomas G Pickering
Joseph E Schwartz
William Gerin
Stony Brook University · USColumbia University Irving Medical Center · USPennsylvania State University · US

Funding

WORKSITE BLOOD PRESSURE STUDYP01HL047540 · NHLBI · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI SCHWARTZ, JOSEPH E · 1993 to 2014
$27.7M
MIND-BODY-BEHAVIORAL MED CLINICAL TRIALS INFRASTRUCTURER24HL076857 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI DAVIDSON, KARINA W. · 2004 to 2008
$3.5M
Translational Study of Hostility, Atherothrombosis &CADK23HL072866 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHIMBO, DAICHI · 2003 to 2007
$774k
NHLBI NIH HHS HL072866NHLBI NIH HHS HL47540NHLBI NIH HHS HL76857NHLBI NIH HHS K23 HL072866NHLBI NIH HHS P01 HL047540NHLBI NIH HHS R24 HL076857
6 · The paper itself

Abstract

objectivesAn algorithm for making a differential diagnosis between sustained and white coat hypertension (WCH) has been proposed - patients with office hypertension undergo home blood pressure monitoring (HBPM) and those with normal HBP levels undergo ambulatory blood pressure monitoring (ABPM). We tested whether incorporating an upper office blood pressure (OBP) cut-off in the algorithm, higher than the traditional 140/90 mmHg, reduces the need for HBPM and ABPM.

methodsTwo hundred twenty-nine normotensive and untreated mildly hypertensive participants (mean age 52.5 +/- 14.6 years, 54% female participants) underwent OBP measurements, HBPM, and 24-h ABPM. Using the algorithm, sensitivity, specificity, and positive and negative predictive values (PPV, NPV) for sustained hypertension and WCH were assessed. We then modified the algorithm utilizing a systolic and diastolic OBP cut-off at a specificity of 95% for ambulatory hypertension - those with office hypertension but OBP levels below the upper cut-off underwent HBPM and subsequent ABPM, if appropriate.

resultsUsing the original algorithm, sensitivity and PPV for sustained hypertension were 100% and 93.8%, respectively. Despite a specificity of 44.4%, NPV was 100%. These values correspond to specificity, NPV, sensitivity, and PPV for WCH, respectively. Using the modified algorithm, the diagnostic accuracy for sustained hypertension and WCH did not change. However, far fewer participants needed HBPM (29 vs. 84) and ABPM (8 vs. 15).

conclusionIn this sample, the original and modified algorithms are excellent at diagnosing sustained hypertension and WCH. However, the latter requires far fewer participants to undergo HBPM and ABPM. These findings have important implications for the cost-effective diagnosis of sustained hypertension and WCH.

Indexed as

AdultAgedAlgorithmsBlood Pressure Monitoring, AmbulatoryFemaleHumansHypertensionMaleMiddle AgedPredictive Value of Tests

Identifiers

PMID19491703
PMCPMC2761950
OpenAlexW1972375259

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.