Evidence map›Paper›PMID 19490364›Full record

ArticleJournal of medical primatology2009

High-risk pregnancy in rhesus monkeys (Macaca mulatta): a case of ectopic, abdominal pregnancy with birth of a live, term infant, and a case of gestational diabetes complicated by pre-eclampsia.

Lisa Krugner-Higby, Melissa Luck, Deborah Hartley, Heather M Crispen, Gabriele R Lubach, Christopher L Coe

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of medical primatology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lisa Krugner-HigbyResearch Animal Resources Center, University of Wisconsin-Madison, Madison, WI, USA. lisakh@rarc.wisc.edu
Melissa Luck
Deborah Hartley
Heather M Crispen
Gabriele R Lubach
Christopher L Coe
University of Wisconsin–Madison · US

Funding

STATISTICAL COREP01HD039386 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LOZOFF, BETSY · 2001 to 2011
$14.0M
Maternal Flu Infection and Brain Development in PrimatesR01AI067518 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI COE, CHRISTOPHER L · 2006 to 2010
$2.3M
PRENATAL STRESS AND IMMUNE RESPONSIVENESSR01AI046521 · NIAID · UNIVERSITY OF WISCONSIN MADISON · PI COE, CHRISTOPHER L. · 2000 to 2004
$1.8M
NIAID NIH HHS AI067518NIAID NIH HHS AI46521NIAID NIH HHS R01 AI046521NIAID NIH HHS R01 AI067518NICHD NIH HHS HD39386NICHD NIH HHS P01 HD039386
6 · The paper itself

Abstract

backgroundCases of abdominal pregnancy, in the form of intra-abdominal mummified fetuses, have been described in nonhuman primates. Gestational diabetes and pre-eclampsia are common pregnancy complications in women.

methodsTwo timed-bred rhesus monkeys had high-risk pregnancies, an abdominal pregnancy with delivery of a live term infant, and a case of gestational diabetes that later developed pre-eclampsia.

resultsThe monkey that had abdominal pregnancy later died from septic peritonitis. The monkey had a colonic adenocarcinoma that may have allowed leakage of intestinal contents into the abdomen. Her infant was fostered to another female and survived. The monkey with gestational diabetes and pre-eclampsia was treated with a regimen similar to that used in women, and a live infant was delivered at day 157 of gestation by Caesarian section.

conclusionThese cases underscore the value of timed-breeding and the similarities between pregnancy complications in women and in nonhuman primates.

Indexed as

Macaca mulattaAnimalsCesarean SectionDiabetes, GestationalFemalePre-EclampsiaPregnancyPregnancy, AbdominalPregnancy, High-Risk

Identifiers

PMID19490364
PMCPMC2711216
OpenAlexW2141914854

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.