ArticleBiophysical journal2009
Phase-state dependent current fluctuations in pure lipid membranes.
Article in Biophysical journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Interleaflet Translocation of Second-Harmonic-Generation-Active Dye Molecules in Phospholipid Bilayers with Transmembrane Pores.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Sharp, localized phase transitions in single neuronal cells.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The activity of the intrinsically water-soluble enzyme ADAMTS13 correlates with the membrane state when bound to a phospholipid bilayer.Scientific reports · 2021Article
- Lipid Membrane State Change by Catalytic Protonation and the Implications for Synaptic Transmission.Membranes · 2021Article
- Non-linear Conductance, Rectification, and Mechanosensitive Channel Formation of Lipid Membranes.Frontiers in cell and developmental biology · 2020Article
- Ultrasound Neuromodulation: A Review of Results, Mechanisms and Safety.Ultrasound in medicine & biology · 2019Review
- Coupling of Membrane Nanodomain Formation and Enhanced Electroporation near Phase Transition.Biophysical journal · 2019Article
- Similarities between action potentials and acoustic pulses in a van der Waals fluid.Scientific reports · 2019Article
- Engineering thermoresponsive phase separated vesicles formedChemical science · 2018Article
- Erlang flow of hydrophilic pore formation and closure events in a lipid bilayer during phase transition resulting from diffusion in the radius space.European biophysics journal : EBJ · 2018Article
- Cell Surface Deformation during an Action Potential.Biophysical journal · 2018Article
- On the excitation of action potentials by protons and its potential implications for cholinergic transmission.Protoplasma · 2016Article
- Evidence for two-dimensional solitary sound waves in a lipid controlled interface and its implications for biological signalling.Journal of the Royal Society, Interface · 2014Article
- Temperature and excitable cells: Testable predictions from a thermodynamic perspective.Communicative & integrative biology · 2013Article
- Voltage-Gated Lipid Ion Channels.PloS one · 2013Article
- The influence of non polar and polar molecules in mouse motile cells membranes and pure lipid bilayers.PloS one · 2013Article
- Article
- Photoactivation of neurons by laser-generated local heating.AIP advances · 2012Article
- Chemical and mechanical impact of silica nanoparticles on the phase transition behavior of phospholipid membranes in theory and experiment.Biophysical journal · 2012Article
- The stability of solitons in biomembranes and nerves.The European physical journal. E, Soft matter · 2011Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current fluctuations in pure lipid membranes have been shown to occur under the influence of transmembrane electric fields (electroporation) as well as a result from structural rearrangements of the lipid bilayer during phase transition (soft perforation). We demonstrate that the ion permeability during lipid phase transition exhibits the same qualitative temperature dependence as the macroscopic heat capacity of a D15PC/DOPC vesicle suspension. Microscopic current fluctuations show distinct characteristics for each individual phase state. Although current fluctuations in the fluid phase show spikelike behavior of short timescales (approximately 2 ms) with a narrow amplitude distribution, the current fluctuations during lipid phase transition appear in distinct steps with timescales of approximately 20 ms. We propose a theoretical explanation for the origin of timescales and permeability based on a linear relationship between lipid membrane susceptibilities and relaxation times near the phase transition.
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