Evidence map›Paper›PMID 19485947›Full record

ArticleBosnian journal of basic medical sciences2009

Action of propranolol in the reaction of smooth musculature of tracheal rings induced with acetylcholine, histamine, serotonin (5-HT) and prostaglandin (PGF2-alfa) in vitro and in vivo.

Hilmi Islami, Sadi Bexheti, Halil Ahmetaj, Aziz Sukalo, Suzana Manxhuka, Bajram Nuraj, Xhevat Kamberi, Shaip Krasniqi, Hasime Qorraj, Bashkim Kastrati and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Bosnian journal of basic medical sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Evaluation of Preclinical and Clinical Studies Published in Medical Journals of Bosnia and Herzegovina: Methodology Issues.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hilmi IslamiDepartment of Pharmacology, Faculty of Medicine, University of Prishtina, Clinical Centre N.N., Prishtina, Kosovo.
Sadi Bexheti
Halil Ahmetaj
Aziz Sukalo
Suzana Manxhuka
Bajram Nuraj
Xhevat Kamberi
Shaip Krasniqi
Hasime Qorraj
Bashkim Kastrati
Mentor Disha
University of Prishtina · XK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Actions of acetylcholine (ACh), histamines, serotonins (5-HT) and prostaglandins (PGF2-alfa) in concentrations of 10(-4), 10(-3), 10(-2) and 10(-1) mol/dm(3) were analyzed in vitro conditions in isolated specimens of tracheas of 24 pigs, 7 guinea pigs, and dead persons for different reasons (8), in the presence and without presence of propranolol. Whilst, research regarding actions of aerosolized histamines (10 mg, 1%, 2 min), in the presence and without the presence of aerosolized propranolol (20 mg, 2%, 2 min) was done in vivo in 6 healthy persons. Study results show that propranolol does not emphasize contraction of the airways smooth musculature as induced by ACh, histamine, 5-HT and PGF2-alfa in vitro conditions (p>0,1). Also, in vivo we found a non-significance of tracheal smooth musculature constriction (p>0,1).

Indexed as

AcetylcholineAnimalsDinoprostGuinea PigsHistamineIn Vitro TechniquesMuscle ContractionMuscle, SmoothPropranololSerotoninSwineAcetylcholineDinoprostHistaminePropranololSerotonin

Identifiers

PMID19485947
PMCPMC5638219
OpenAlexW2417745604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.