ArticlePlant physiology2009
The role of annexin 1 in drought stress in Arabidopsis.
Article in Plant physiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 1 of them a synthesis that pooled it.
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Who cites it
102 citing papers in PubMed, 1 synthesis or guideline pooled it, 242 citations in OpenAlex.
- Pearl millet response to drought: A review.Frontiers in plant science · 2023Pooled it
- Comprehensive Analysis of Annexin Family fromPlants (Basel, Switzerland) · 2026Article
- Linking redox and calcium signaling via thioredoxins.Journal of experimental botany · 2026Review
- Divergent Transcriptional Architectures Beyond Core CAM Genes in Facultative and Constitutive CAM Species in Tillandsia L.Molecular ecology · 2026Article
- Molecular resilience: genetic analysis of multiple-stress tolerance (osmotic, salinity, cold and heat) during potato (Frontiers in plant science · 2026Article
- Genome-Wide Identification and In Silico Analysis of Annexins in Chickpea (Cicer arietinum L.).Biochemical genetics · 2025Article
- Function and evolution of plant annexins in response to abiotic stresses.BMC plant biology · 2025Review
- Genome-Wide Characterization of thePlants (Basel, Switzerland) · 2025Article
- Annexins: central regulators of plant growth and stress signaling.Acta biochimica et biophysica Sinica · 2025Review
- Integrated multi-omics analysis reveals drought stress response mechanism in chickpea (Cicer arietinum L.).The plant genome · 2024Article
- Comprehensive analysis of annexin gene family and its expression in response to branching architecture and salt stress in crape myrtle.BMC plant biology · 2024Article
- The Wheat AnnexinInternational journal of molecular sciences · 2023Article
- The rice annexin genePlant direct · 2023Article
- Calcium-binding protein OsANN1 regulates rice blast disease resistance by inactivating jasmonic acid signaling.Plant physiology · 2023Article
- Multiple cyclic nucleotide-gated channels function as ABA-activated Ca2+ channels required for ABA-induced stomatal closure in Arabidopsis.The Plant cell · 2023Article
- GmWAK1, Novel Wall-Associated Protein Kinase, Positively Regulates Response of Soybean toInternational journal of molecular sciences · 2023Article
- Article
- Candidate regulators of drought stress in tomato revealed by comparative transcriptomic and proteomic analyses.Frontiers in plant science · 2023Article
- Physiological and Proteomic Responses of Cassava to Short-Term Extreme Cool and Hot Temperature.Plants (Basel, Switzerland) · 2022Article
- Identification of Candidate Genes Regulating Drought Tolerance in Pearl Millet.International journal of molecular sciences · 2022Article
42 more citing papers are in PubMed but not listed here.
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9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Annexins act as targets of calcium signals in eukaryotic cells, and recent results suggest that they play an important role in plant stress responses. We found that in Arabidopsis (Arabidopsis thaliana), AnnAt1 (for annexin 1) mRNA levels were up-regulated in leaves by most of the stress treatments applied. Plants overexpressing AnnAt1 protein were more drought tolerant and knockout plants were more drought sensitive than ecotype Columbia plants. We also observed that hydrogen peroxide accumulation in guard cells was reduced in overexpressing plants and increased in knockout plants both before and after treatment with abscisic acid. Oxidative protection resulting from AnnAt1 overexpression could be due to the low level of intrinsic peroxidase activity exhibited by this protein in vitro, previously linked to a conserved histidine residue found in a peroxidase-like motif. However, analyses of a mutant H40A AnnAt1 protein in a bacterial complementation test and in peroxidase activity assays indicate that this residue is not critical to the ability of AnnAt1 to confer oxidative protection. To further examine the mechanism(s) linking AnnAt1 expression to stress resistance, we analyzed the reactive S3 cluster to determine if it plays a role in AnnAt1 oligomerization and/or is the site for posttranslational modification. We found that the two cysteine residues in this cluster do not form intramolecular or intermolecular bonds but are highly susceptible to oxidation-driven S-glutathionylation, which decreases the Ca(2+) affinity of AnnAt1 in vitro. Moreover, S-glutathionylation of AnnAt1 occurs in planta after abscisic acid treatment, which suggests that this modification could be important in regulating the cellular function of AnnAt1 during stress responses.
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