Evidence map›Paper›PMID 19482671›Full record

ArticleFrontiers in bioscience (Elite edition)2009

Nuclear localization of ISWI ATPase Smarca5 (Snf2h) in mouse.

Jarmila Vargova, Karina Vargova, Arthur I Skoultchi, Tomas Stopka

Abstract read
In one paragraph

Article in Frontiers in bioscience (Elite edition), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Genome-scale study of transcription factor expression in the branching mouse lung.Developmental dynamics : an official publication of the American Association of Anatomists · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jarmila VargovaPathological Physiology and Center of Experimental Hematology, First Faculty of Medicine, Charles University, Prague, Czech Republic.
Karina Vargova
Arthur I Skoultchi
Tomas Stopka
Charles University · CZ

Funding

Control of Erythroid Cell Division and DifferentiationR01HL078381 · NHLBI · ALBERT EINSTEIN COL OF MED YESHIVA UNIV · PI SKOULTCHI, ARTHUR I · 2004 to 2008
$2.1M
Tailored Computerized Intervention for Behavior ChangeR15NR009021 · NINR · UNIVERSITY OF WISCONSIN MILWAUKEE · PI RYAN, POLLY · 2006 to 2006
$212k
NHLBI NIH HHS HL 78381NHLBI NIH HHS R01 HL078381NINR NIH HHS R15 NR009021
6 · The paper itself

Abstract

Nucleosome movement is, at least in part, facilitated by ISWI ATPase Smarca5 (Snf2h). Smarca5 gene inactivation in mouse demonstrated its requirement at blastocyst stage; however its role at later stages is not completely understood. We herein determined nuclear distribution of Smarca5 and histone marks associated with actively transcribed and repressed chromatin structure in embryonic and adult murine tissues and in tumor cells. Confocal microscopy images demonstrate that Smarca5 is localized mainly in euchromatin and to lesser extent also in heterochromatin and nucleoli. Smarca5 heterozygous mice for a null allele display decreased levels of histone H3 modifications and defects in heterochromatin foci supporting role of Smarca5 as a key regulator of global chromatin structure.

Indexed as

Adenosine TriphosphatasesAnimalsBlastocystCell Line, TumorCell NucleolusChromosomal Proteins, Non-HistoneEuchromatinGene SilencingHeterochromatinMiceMice, Inbred C57BLMicroscopy, ConfocalAdenosine TriphosphatasesChromosomal Proteins, Non-HistoneEuchromatinHeterochromatinSmarca5 protein, mouse

Identifiers

PMID19482671
PMCPMC3556728
OpenAlexW1493706950

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.