Evidence map›Paper›PMID 19482623›Full record

ReviewFrontiers in bioscience (Elite edition)2009

Chemokines and angiogenesis in rheumatoid arthritis.

Zoltan Szekanecz, Angela Pakozdi, Agnes Szentpetery, Timea Besenyei, Alisa E Koch

Open access · greenAbstract readReview
In one paragraph

Review in Frontiers in bioscience (Elite edition), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 62 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Inhibition of Rheumatoid Arthritis Using Bark, Leaf, and Male Flower Extracts ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
  10. Article
  11. Electroacupuncture on ST36 and GB39 Acupoints Inhibits Synovial Angiogenesis via Downregulating HIF-1Evidence-based complementary and alternative medicine : eCAM · 2019
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. The role of TNF-α in rheumatoid arthritis: a focus on regulatory T cells.Journal of clinical and translational research · 2016
    Review
  17. The Role of CC-Chemokines in the Regulation of Angiogenesis.International journal of molecular sciences · 2016
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zoltan SzekaneczDivision of Rheumatology, Third Department of Medicine, University of Debrecen Medical and Health Sciences Center, Debrecen, H-4004, Hungary. szekanecz@iiibel.dote.hu
Angela Pakozdi
Agnes Szentpetery
Timea Besenyei
Alisa E Koch
University of Debrecen · HU

Funding

IL-18 in rheumatoid inflammation and angiogenesisR01AR048267 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOCH, ALISA E · 2003 to 2007
$1.4M
IL 4 AND IL 13 GENE THERAPY FOR ARTHRITISR01AI040987 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI KOCH, ALISA E · 1998 to 2006
$1.3M
IL 4 AND IL 13 GENE THERAPY FOR ARTHRITISR21AI040987 · NIAID · NORTHWESTERN UNIVERSITY · PI KOCH, ALISA E · 1997 to 1997
–
NIAID NIH HHS AI-40987NIAID NIH HHS R01 AI040987NIAMS NIH HHS AR-048267NIAMS NIH HHS R01 AR048267
6 · The paper itself

Abstract

In rheumatoid arthritis, chemokines mediate the migration of inflammatory leukocytes into the synovium. Among the four known chemokine families, CXC, CC chemokines and fractalkine seem to be of outstanding importance in this process. Angiogenesis, the formation of new vessels, is also important during the perpetuation of inflammation underlying rheumatoid arthritis. In this review, authors discuss the role of the most important chemokines and chemokine receptors in arthritis-associated neovascularization. The process and regulation of angiogenesis are described in this context as well. Apart from discussing the pathogenic role of chemokines and chemokine receptors in arthritic vessel formation, authors also review the important relevance of chemokines and angiogenesis for therapeutic intervention.

Indexed as

Arthritis, RheumatoidChemokinesHumansNeovascularization, PathologicReceptors, ChemokineSynovial MembraneChemokinesReceptors, Chemokine

Identifiers

PMID19482623
PMCPMC2884394
OpenAlexW341380709

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.