ReviewInternational journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience2009
Modeling premature brain injury and recovery.
Review in International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
53 citing papers in PubMed, 80 citations in OpenAlex.
- Cerebral Lateralization is Protective in the Very Prematurely Born.Cerebral cortex (New York, N.Y. : 1991) · 2015Trial
- Pharmacokinetics and Brain Distribution of a Purine-Derived Neuroprotective Agent after Intranasal Administration in Neonatal Rats with Hypoxic-Ischemic Brain Injury.Pharmaceutical research · 2026Article
- Glycyrrhizin Attenuates White Matter Injury by Inhibiting Neuroinflammation through the HMGB1/TLR4 Pathway.Molecular neurobiology · 2025Article
- Pharmacogenomic screening identifies and repurposes leucovorin and dyclonine as pro-oligodendrogenic compounds in brain repair.Nature communications · 2024Article
- TrkB-mediated neuroprotection in female hippocampal neurons is autonomous, estrogen receptor alpha-dependent, and eliminated by testosterone: a proposed model for sex differences in neonatal hippocampal neuronal injury.Biology of sex differences · 2024Article
- Inter-Alpha Inhibitor Proteins Modify the Microvasculature after Exposure to Hypoxia-Ischemia and Hypoxia in Neonatal Rats.International journal of molecular sciences · 2023Article
- Oxidative Stress-Induced Damage to the Developing Hippocampus Is Mediated by GSK3β.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Editorial: Perinatal hypoxic-ischemic brain injury: Mechanisms, pathogenesis, and potential therapeutic strategies.Frontiers in cellular neuroscience · 2022Article
- The child with medical complexity.Italian journal of pediatrics · 2021Review
- Disruption and Compensation of Sulcation-based Covariance Networks in Neonatal Brain Growth after Perinatal Injury.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- Effects of early life exposure to traffic-related air pollution on brain development in juvenile Sprague-Dawley rats.Translational psychiatry · 2020Article
- Environmental enrichment ameliorates perinatal brain injury and promotes functional white matter recovery.Nature communications · 2020Article
- Pharmacokinetics of Inter-Alpha Inhibitor Proteins and Effects on Hemostasis After Hypoxic-Ischemic Brain Injury in Neonatal Rats.Current pharmaceutical design · 2020Article
- EPAS 1, congenital heart disease, and high altitude: disclosures by genetics, bioinformatics, and experimental embryology.Bioscience reports · 2019Article
- High-mobility group box-1 translocation and release after hypoxic ischemic brain injury in neonatal rats.Experimental neurology · 2019Article
- Ontogeny of white matter, toll-like receptor expression, and motor skills in the neonatal ferret.International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience · 2018Article
- Enhanced autophagy contributes to excitotoxic lesions in a rat model of preterm brain injury.Cell death & disease · 2018Article
- Brain Metabolism Alterations Induced by Pregnancy Swimming Decreases Neurological Impairments Following Neonatal Hypoxia-Ischemia in Very Immature Rats.Frontiers in neurology · 2018Article
- Neonatal Dexamethasone Treatment Exacerbates Hypoxia/Ischemia-Induced White Matter Injury.Molecular neurobiology · 2017Article
- White matter injury in the preterm infant: pathology and mechanisms.Acta neuropathologica · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Premature birth is a growing and significant public health problem because of the large number of infants that survive with neurodevelopmental sequelae from brain injury. Recent advances in neuroimaging have shown that although some neuroanatomical structures are altered, others improve over time. This review outlines recent insights into brain structure and function in these preterm infants at school age and relevant animal models. These animal models have provided scientists with an opportunity to explore in depth the molecular and cellular mechanisms of injury as well as the potential of the brain for recovery. The endogenous potential that the brain has for neurogenesis and gliogenesis, and how environment contributes to recovery, are also outlined. These preclinical models will provide important insights into the genetic and epigenetic mechanisms responsible for variable degrees of injury and recovery, permitting the exploration of targeted therapies to facilitate recovery in the developing preterm brain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.