ArticleSleep2009
The time course of the probability of transition into and out of REM sleep.
Article in Sleep, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed.
- A data-driven measure of REM sleep propensity for human and rodent sleep.Frontiers in neuroscience · 2026Article
- A predictive propensity measure to enter REM sleep.Frontiers in neuroscience · 2024Article
- A probabilistic model for the ultradian timing of REM sleep in mice.PLoS computational biology · 2021Article
- Neural and Homeostatic Regulation of REM Sleep.Frontiers in psychology · 2020Review
- The temporal structure of behaviour and sleep homeostasis.PloS one · 2012Article
- Reduced γ range activity at REM sleep onset and termination in fear-conditioned Wistar-Kyoto rats.Neuroscience letters · 2011Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesA model of rapid eye movement (REM) sleep expression is proposed that assumes underlying regulatory mechanisms operating as inhomogenous Poisson processes, the overt results of which are the transitions into and out of REM sleep.
designBased on spontaneously occurring REM sleep episodes ("Episode") and intervals without REM sleep ("Interval"), 3 variables are defined and evaluated over discrete 15-second epochs using a nonlinear logistic regression method: "Propensity" is the instantaneous rate of into-REM transition occurrence throughout an Interval, "Volatility" is the instantaneous rate of out-of-REM transition occurrence throughout an Episode, and "Opportunity" is the probability of being in non-REM (NREM) sleep at a given time throughout an Interval, a requisite for transition.
setting12:12 light:dark cycle, isolated boxes.
participantsSixteen male Sprague-Dawley rats.
interventionsNone. Spontaneous sleep cycles. MEASUREMENTS AND
resultsThe highest levels of volatility and propensity occur, respectively, at the very beginning of Episodes and Intervals. The new condition stabilizes rapidly, and variables reach nadirs at minute 1.25 and 2.50, respectively. Afterward, volatility increases markedly, reaching values close to the initial level. Propensity increases moderately, the increment being stronger through NREM sleep bouts occurring at the end of long Intervals. Short-term homeostasis is evidenced by longer REM sleep episodes lowering propensity in the following Interval.
conclusionsThe stabilization after transitions into Episodes or Intervals and the destabilization after remaining for some time in either condition may be described as resulting from continuous processes building up during Episodes and intervals. These processes underlie the overt occurrence of transitions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.