ArticleNeurorehabilitation and neural repair2009
Repeated maximal volitional effort contractions in human spinal cord injury: initial torque increases and reduced fatigue.
Article in Neurorehabilitation and neural repair, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 36 citations in OpenAlex.
- Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury.Genome medicine · 2025Trial
- Task-Specific Versus Impairment-Based Training on Locomotor Performance in Individuals With Chronic Spinal Cord Injury: A Randomized Crossover Study.Neurorehabilitation and neural repair · 2020Trial
- Exercise-Induced Alterations in Sympathetic-Somatomotor Coupling in Incomplete Spinal Cord Injury.Journal of neurotrauma · 2019Trial
- Divergent modulation of clinical measures of volitional and reflexive motor behaviors following serotonergic medications in human incomplete spinal cord injury.Journal of neurotrauma · 2013Trial
- Methods to quantify pharmacologically induced alterations in motor function in human incomplete SCI.Journal of visualized experiments : JoVE · 2011Trial
- Intermittent hypoxia enhances voluntary activation and reduces performance fatigability during repeated lower limb contractions.Journal of neurophysiology · 2024Article
- Validity and Reliability of Surface Electromyography Features in Lower Extremity Muscle Contraction in Healthy and Spinal Cord-Injured Participants.Topics in spinal cord injury rehabilitation · 2021Article
- Repeated and patterned stimulation of cutaneous reflex pathways amplifies spinal cord excitability.Journal of neurophysiology · 2020Article
- Modification of a three-compartment muscle fatigue model to predict peak torque decline during intermittent tasks.Journal of biomechanics · 2018Article
- Strategies to augment volitional and reflex function may improve locomotor capacity following incomplete spinal cord injury.Journal of neurophysiology · 2018Review
- The Relationship Between Volitional Activation and Muscle Properties in Incomplete Spinal Cord Injury.Topics in spinal cord injury rehabilitation · 2018Article
- Metabolic and Fatigue Profiles Are Comparable Between Prepubertal Children and Well-Trained Adult Endurance Athletes.Frontiers in physiology · 2018Article
- Increased spinal reflex excitability is associated with enhanced central activation during voluntary lengthening contractions in human spinal cord injury.Journal of neurophysiology · 2015Article
- Mechanisms underlying chronic whiplash: contributions from an incomplete spinal cord injury?Pain medicine (Malden, Mass.) · 2014Article
- Quadriceps muscle weakness, activation deficits, and fatigue with Parkinson disease.Neurorehabilitation and neural repair · 2012Article
- Central excitability contributes to supramaximal volitional contractions in human incomplete spinal cord injury.The Journal of physiology · 2011Article
- Physical therapy intervention for a former power lifter after arthroscopic microfracture procedure for grade iv glenohumeral chondral defects.International journal of sports physical therapy · 2011Article
- The promise of mHealth: daily activity monitoring and outcome assessments by wearable sensors.Neurorehabilitation and neural repairReview
- Potential associations between chronic whiplash and incomplete spinal cord injury.Spinal cord series and casesArticle
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundSubstantial data indicate greater muscle fatigue in individuals with spinal cord injury (SCI) compared with healthy control subjects when tested by using electrical stimulation protocols. Few studies have investigated the extent of volitional fatigue in motor incomplete SCI.
methodsRepeated, maximal volitional effort (MVE) isometric contractions of the knee extensors (KE) were performed in 14 subjects with a motor incomplete SCI and in 10 intact subjects. Subjects performed 20 repeated, intermittent MVEs (5 seconds contraction/5 seconds rest) with KE torques and thigh electromyographic (EMG) activity recorded.
resultsPeak KE torques declined to 64% of baseline MVEs with repeated efforts in control subjects. Conversely, subjects with SCI increased peak torques during the first 5 contractions by 15%, with little evidence of fatigue after 20 repeated efforts. Increases in peak KE torques and the rate of torque increase during the first 5 contractions were attributed primarily to increases in quadriceps EMG activity, but not to decreased knee flexor co-activation. The observed initial increases in peak torque were dependent on the subject's volitional activation and were consistent on the same or different days, indicating little contribution of learning or accommodation to the testing conditions. Sustained MVEs did not elicit substantial increases in peak KE torques as compared to repeated intermittent efforts.
conclusionsThese data revealed a marked divergence from expected results of increased fatigability in subjects with SCI, and may be a result of complex interactions between mechanisms underlying spastic motor activity and changes in intrinsic motoneuron properties.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.