Evidence map›Paper›PMID 19477148›Full record

ArticleNeuron2009

Tyramine: a new receptor and a new role at the synapse.

Robyn Branicky, Wiliam R Schafer

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Robyn BranickyCell Biology Division, MRC Laboratory of Molecular Biology, Cambridge, UK. rsb@mrc-lmb.cam.ac.uk
Wiliam R Schafer
MRC Laboratory of Molecular Biology · GB

Funding

Medical Research Council MC_U105185857
6 · The paper itself

Abstract

Biogenic amines are typically regarded as neuromodulators rather than fast-acting neurotransmitters. In this issue of Neuron, Pirri et al. report the characterization of LGC-55 in C. elegans, the first identified tyramine-gated chloride channel. This study suggests that the roles of classical and trace biogenic amines in all organisms may need to be reconsidered.

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsReceptors, Biogenic AmineSynapsesCaenorhabditis elegans ProteinsReceptors, Biogenic Aminetyramine receptor

Identifiers

PMID19477148
OpenAlexW2082548725

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.