ArticleFertility and sterility2010
Serum leptin levels, hormone levels, and hot flashes in midlife women.
Article in Fertility and sterility, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 45 citations in OpenAlex.
- Visfatin correlates with hot flashes in postmenopausal women with metabolic syndrome: effects of genistein.Endocrine · 2017Trial
- An intensive behavioral weight loss intervention and hot flushes in women.Archives of internal medicine · 2010Trial
- Subjective menopausal hot flashes in sleep disturbance: does the timing of hot flashes matter?Menopause (New York, N.Y.) · 2026Article
- Comparison of leptin and estrone levels between normal body mass index and obese menopausal women.Narra J · 2024Article
- Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1.GeroScience · 2024Article
- Current Perspectives: Obesity and Neurodegeneration - Links and Risks.Degenerative neurological and neuromuscular disease · 2023Review
- Metabolically healthy and unhealthy obesity and risk of vasomotor symptoms in premenopausal women: cross-sectional and cohort studies.BJOG : an international journal of obstetrics and gynaecology · 2022Article
- Perimenopause, body fat, metabolism and menopausal symptoms in relation to serum markers of adiposity, inflammation and digestive metabolism.Journal of endocrinological investigation · 2020Article
- Association of hot flushes with ghrelin and adipokines in early versus late postmenopausal women.Menopause (New York, N.Y.) · 2020Article
- Paeonol, an Ingredient of Kamishoyosan, Reduces Intracellular Lipid Accumulation by Inhibiting Glucocorticoid Receptor Activity in 3T3-L1 Cells.Nutrients · 2020Article
- The Impact of Hormonal Imbalances Associated with Obesity on the Incidence of Endometrial Cancer in Postmenopausal Women.Journal of Cancer · 2020Review
- The Midlife Women's Health Study - a study protocol of a longitudinal prospective study on predictors of menopausal hot flashes.Women's midlife health · 2017Article
- Circulating leptin and adiponectin are associated with insulin resistance in healthy postmenopausal women with hot flashes.PloS one · 2017Article
- Menopausal vasomotor symptoms and incident breast cancer risk in the Study of Women's Health Across the Nation.Cancer causes & control : CCC · 2016Article
- Association of Mid-Life Changes in Body Size, Body Composition and Obesity Status with the Menopausal Transition.Healthcare (Basel, Switzerland) · 2016Review
- The impact of leptin on perinatal development and psychopathology.Journal of chemical neuroanatomy · 2014Review
- Adipokines, adiposity, and vasomotor symptoms during the menopause transition: findings from the Study of Women's Health Across the Nation.Fertility and sterility · 2013Article
- Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women.Obesity (Silver Spring, Md.) · 2013Article
- Effects of a dietary intervention and weight change on vasomotor symptoms in the Women's Health Initiative.Menopause (New York, N.Y.) · 2012Article
- Vasomotor symptoms and menopause: findings from the Study of Women's Health across the Nation.Obstetrics and gynecology clinics of North America · 2011Review
Corrections and comments
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Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
objectiveTo examine the associations between serum leptin levels, sex steroid hormone levels, and hot flashes in normal weight and obese midlife women.
designCross-sectional study.
settingUniversity clinic. PATIENT(S): 201 Caucasian, nonsmoking women aged 45 to 54 years with a body mass index of <25 kg/m2 or >or=30 kg/m2. INTERVENTION(S): Questionnaire, fasting blood samples. MAIN OUTCOME MEASURE(S): Serum leptin and sex steroid hormone levels. RESULT(S): Correlation and regression models were performed to examine associations between leptin levels, hormone levels, and hot flashes. Leptin levels were associated with BMI, with "ever experiencing hot flashes" (questionnaire), with hot flashes within the last 30 days, and with duration of hot flashes (>1 year, P=.03). Leptin was positively correlated with testosterone, free testosterone index, and free estrogen index and inversely associated with levels of sex hormone-binding globulin. In women with a body mass index>or=30 kg/m2, leptin levels no longer correlated with testosterone levels. CONCLUSION(S): Serum leptin levels are associated with the occurrence and duration of hot flashes in midlife women; however, no correlation was found between leptin and serum estradiol.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.