Trial reportJournal of general internal medicine2009
Reducing the prescribing of heavily marketed medications: a randomized controlled trial.
Trial report in Journal of general internal medicine, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00788346 (Reducing Unnecessary Use of Heavily Marketed Medicines), which is not on this map. Cited by 14 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Reducing Unnecessary Use of Heavily Marketed Medicines: A Randomized Controlled Trial of Computerized Prescribing Alerts and Clinician Education
Who cites it
14 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Academic Detailing Interventions and Evidence-Based Prescribing: A Systematic Review.JAMA network open · 2025Pooled it
- Electronic Health Record Nudges and Health Care Quality and Outcomes in Primary Care: A Systematic Review.JAMA network open · 2024Pooled it
- Conceptualizing clinical decision support as complex interventions: a meta-analysis of comparative effectiveness trials.Journal of the American Medical Informatics Association : JAMIA · 2022Pooled it
- What maximizes the effectiveness and implementation of technology-based interventions to support healthcare professional practice? A systematic literature review.BMC medical informatics and decision making · 2018Pooled it
- Pooled it
- Risks to patient safety associated with implementation of electronic applications for medication management in ambulatory care--a systematic review.BMC medical informatics and decision making · 2013Pooled it
- Computerized clinical decision support systems for drug prescribing and management: a decision-maker-researcher partnership systematic review.Implementation science : IS · 2011Pooled it
- The effects of on-screen, point of care computer reminders on processes and outcomes of care.The Cochrane database of systematic reviews · 2009Pooled it
- The effectiveness of integrated health information technologies across the phases of medication management: a systematic review of randomized controlled trials.Journal of the American Medical Informatics Association : JAMIAPooled it
- Article
- Addressing Barriers to Reducing Prescribing and Implementing Deprescribing of Sedative-Hypnotics in Primary Care.The Annals of pharmacotherapy · 2022Article
- The GUIDES checklist: development of a tool to improve the successful use of guideline-based computerised clinical decision support.Implementation science : IS · 2018Article
- Drug incompatibilities in the adult intensive care unit of a university hospital.Revista Brasileira de terapia intensiva · 2016Article
- Can automated alerts within computerized physician order entry improve compliance with laboratory practice guidelines for ordering Pap tests?Journal of pathology informatics · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
contextPrescription drug costs are a major component of health care expenditures, yet resources to support evidence-based prescribing are not widely available.
objectiveTo evaluate the effectiveness of computerized prescribing alerts, with or without physician-led group educational sessions, to reduce the prescribing of heavily marketed hypnotic medications.
designCluster-randomized controlled trial.
settingWe randomly allocated 14 internal medicine practice sites to receive usual care, computerized prescribing alerts alone, or alerts plus group educational sessions. MEASUREMENTS: Proportion of heavily marketed hypnotics prescribed before and after the implementation of computerized alerts and educational sessions. MAIN
resultsThe activation of computerized alerts held the prescribing of heavily marketed hypnotic medications at pre-intervention levels in both the alert-only group (adjusted risk ratio [RR] 0.97; 95% CI 0.82-1.14) and the alert-plus-education group (RR 0.98; 95% CI 0.83-1.17) while the usual-care group experienced an increase in prescribing (RR 1.31; 95% CI 1.08-1.60). Compared to the usual-care group, the relative risk of prescribing heavily marketed medications was less in both the alert-group (Ratio of risk ratios [RRR] 0.74; 95% CI 0.57-0.96) and the alert-plus-education group (RRR 0.74; 95% CI 0.58-0.97). The prescribing of heavily marketed medications was similar in the alert-group and alert-plus-education group (RRR 1.02; 95% CI 0.80-1.29). Most clinicians reported that the alerts provided useful prescribing information (88%) and did not interfere with daily workflow (70%).
conclusionsComputerized decision support is an effective tool to reduce the prescribing of heavily marketed hypnotic medications in ambulatory care settings.
trial registrationclinicaltrials.gov Identifier: NCT00788346.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.