ArticleClinical and vaccine immunology : CVI2009
Immunological profiles of Bos taurus and Bos indicus cattle infested with the cattle tick, Rhipicephalus (Boophilus) microplus.
Article in Clinical and vaccine immunology : CVI, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
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Who cites it
49 citing papers in PubMed, 122 citations in OpenAlex.
- A Nelore Cattle Structural Variant Catalog.Animal genetics · 2026Article
- Immune responses of Bos indicus versus Bos taurus cattle towards Bluetongue virus or Schmallenberg virus differ significantly.Communications biology · 2026Article
- First evaluation of the efficacy and operational cost of acaricidal bath combining different droplet sizes, pressures and spray patterns in dairy cows naturally infested with Rhipicephalus microplus.Tropical animal health and production · 2025Article
- Depicting "arms race" of Rhipicephalus microplus and its host on a single frame platform.Parasitology research · 2025Article
- Editorial: Skin - confluence of vertebrate host defences, arthropod vectors, and vector-borne pathogens.Frontiers in immunology · 2025Article
- Two protocols using fluralaner for Rhipicephalus microplus strategic control on taurine cattle in a tropical region.Parasites & vectors · 2024Article
- Perspectives on using integrated tick management to controlFrontiers in veterinary science · 2024Article
- The potential for use of haematological and anti-IgE humoral responses as phenotypic markers for tick resistance in cattle.Current research in parasitology & vector-borne diseases · 2024Article
- More than Three Decades of Bm86: What We Know and Where to Go.Pathogens (Basel, Switzerland) · 2023Review
- Population dynamics of Rhipicephalus microplus in dairy cattle: influence of the animal categories and correlation with milk production.Veterinary research communications · 2023Article
- The Economic Impact of Parasitism from Nematodes, Trematodes and Ticks on Beef Cattle Production.Animals : an open access journal from MDPI · 2023Review
- Application of quantitative proteomics to discover biomarkers for tick resistance in cattle.Frontiers in immunology · 2023Article
- Transcriptional changes in the peripheral blood leukocytes from Brangus cattle before and after tick challenge with Rhipicephalus australis.BMC genomics · 2022Article
- Genome variation in tick infestation and cryptic divergence in Tunisian indigenous sheep.BMC genomics · 2022Article
- Expression of cytokines in dairy cattle mammary gland parenchyma during chronic staphylococcal infection.Veterinary research · 2021Article
- From Bench to Field: A Guide to Formulating and Evaluating Anti-Tick Vaccines Delving beyond Efficacy to Effectiveness.Vaccines · 2021Review
- Review
- Tick host immunity: vector immunomodulation and acquired tick resistance.Trends in immunology · 2021Review
- Tick Infestation and Piroplasm Infection in Barbarine and Queue Fine de l'Ouest Autochthonous Sheep Breeds in Tunisia, North Africa.Animals : an open access journal from MDPI · 2021Article
- Multiple Country and Breed Genomic Prediction of Tick Resistance in Beef Cattle.Frontiers in immunology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cattle tick, Rhipicephalus (Boophilus) microplus, is a major threat to the improvement of cattle production in tropical and subtropical countries worldwide. Bos indicus cattle are naturally more resistant to infestation with the cattle tick than are Bos taurus breeds, although considerable variation in resistance occurs within and between breeds. It is not known which genes contribute to the resistant phenotype, nor have immune parameters involved in resistance to R. microplus been fully described for the bovine host. This study was undertaken to determine whether selected cellular and antibody parameters of the peripheral circulation differed between tick-resistant Bos indicus and tick-susceptible Bos taurus cattle following a period of tick infestations. This study demonstrated significant differences between the two breeds with respect to the percentage of cellular subsets comprising the peripheral blood mononuclear cell population, cytokine expression by peripheral blood leukocytes, and levels of tick-specific immunoglobulin G1 (IgG1) antibodies measured in the peripheral circulation. In addition to these parameters, the Affymetrix bovine genome microarray was used to analyze gene expression by peripheral blood leukocytes of these animals. The results demonstrate that the Bos indicus cattle developed a stabilized T-cell-mediated response to tick infestation evidenced by their cellular profile and leukocyte cytokine spectrum. The Bos taurus cattle demonstrated cellular and gene expression profiles consistent with a sustained innate, inflammatory response to infestation, although high tick-specific IgG1 titers suggest that these animals have also developed a T-cell response to infestation.
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