ArticleGenetics2009
Sexual isolation in Acinetobacter baylyi is locus-specific and varies 10,000-fold over the genome.
Article in Genetics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- DNA modifications impact natural transformation of Acinetobacter baumannii.Nucleic acids research · 2023Article
- Collection of Annotated Acinetobacter Genome Sequences.Microbiology resource announcements · 2023Article
- Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis.Biochemical Society transactions · 2020Review
- Cell-Free DNA: An Underestimated Source of Antibiotic Resistance Gene Dissemination at the Interface Between Human Activities and Downstream Environments in the Context of Wastewater Reuse.Frontiers in microbiology · 2020Review
- Competence for Natural Transformation Is Common among Clinical Strains of ResistantMicroorganisms · 2019Article
- A genomic view of experimental intraspecies and interspecies transformation of a rifampicin-resistance allele into Neisseria meningitidis.Microbial genomics · 2018Article
- Lateral Antimicrobial Resistance Genetic Transfer is active in the open environment.Scientific reports · 2017Article
- Costs and benefits of natural transformation in Acinetobacter baylyi.BMC microbiology · 2017Article
- Steady at the wheel: conservative sex and the benefits of bacterial transformation.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- The Landscape of Realized Homologous Recombination in Pathogenic Bacteria.Molecular biology and evolution · 2016Article
- Growth phase-specific evolutionary benefits of natural transformation in Acinetobacter baylyi.The ISME journal · 2015Article
- Gene transfer potential of outer membrane vesicles of Acinetobacter baylyi and effects of stress on vesiculation.Applied and environmental microbiology · 2014Article
- Extensive cotransformation of natural variation into chromosomes of naturally competent Haemophilus influenzae.G3 (Bethesda, Md.) · 2014Article
- Detecting rare gene transfer events in bacterial populations.Frontiers in microbiology · 2014Review
- Fitness costs of various mobile genetic elements in Enterococcus faecium and Enterococcus faecalis.The Journal of antimicrobial chemotherapy · 2013Article
- Identical miniature inverted repeat transposable elements flank class 1 integrons in clinical isolates of Acinetobacter spp.Journal of clinical microbiology · 2013Article
- An investigation of horizontal transfer of feed introduced DNA to the aerobic microbiota of the gastrointestinal tract of rats.BMC research notes · 2012Article
- A trade-off between the fitness cost of functional integrases and long-term stability of integrons.PLoS pathogens · 2012Article
- Natural transformation facilitates transfer of transposons, integrons and gene cassettes between bacterial species.PLoS pathogens · 2012Article
- Transformation of natural genetic variation into Haemophilus influenzae genomes.PLoS pathogens · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Naturally transformable bacteria acquire chromosomal DNA from related species at lower frequencies than from cognate DNA sources. To determine how genome location affects heterogamic transformation in bacteria, we inserted an nptI marker into random chromosome locations in 19 different strains of the Acinetobacter genus (>24% divergent at the mutS/trpE loci). DNA from a total of 95 nptI-tagged isolates was used to transform the recipient Acinetobacter baylyi strain ADP1. A total of >1300 transformation assays revealed that at least one nptI-tagged isolate for each of the strains/species tested resulted in detectable integration of the nptI marker into the ADP1 genome. Transformation frequencies varied up to approximately 10,000-fold among independent nptI insertions within a strain. The location and local sequence divergence of the nptI flanking regions were determined in the transformants. Heterogamic transformation depended on RecA and was hampered by DNA mismatch repair. Our studies suggest that single-locus-based studies, and inference of transfer frequencies from general estimates of genomic sequence divergence, is insufficient to predict the recombination potential of chromosomal DNA fragments between more divergent genomes. Interspecies differences in overall gene content, and conflicts in local gene organization and synteny are likely important determinants of the genomewide variation in recombination rates between bacterial species.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.