ArticleJournal of neurophysiology2009
Tone-specific and nonspecific plasticity of inferior colliculus elicited by pseudo-conditioning: role of acetylcholine and auditory and somatosensory cortices.
Article in Journal of neurophysiology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 28 citations in OpenAlex.
- Mixed Representations of Sound and Action in the Auditory Midbrain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Cholinergic modulation in the vertebrate auditory pathway.Frontiers in cellular neuroscience · 2024Review
- Mixed representations of sound and action in the auditory midbrain.bioRxiv : the preprint server for biology · 2023Article
- Cholinergic Boutons are Distributed Along the Dendrites and Somata of VIP Neurons in the Inferior Colliculus.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- αFrontiers in neural circuits · 2021Article
- Embracing Complexity in Defensive Networks.Neuron · 2019Review
- Auditory midbrain coding of statistical learning that results from discontinuous sensory stimulation.PLoS biology · 2018Article
- Auditory fear conditioning modifies steady-state evoked potentials in the rat inferior colliculus.Journal of neurophysiology · 2017Article
- Identification of Candidate Allosteric Modulators of the M1 Muscarinic Acetylcholine Receptor Which May Improve Vagus Nerve Stimulation in Chronic Tinnitus.Frontiers in neuroscience · 2017Article
- Suppression and facilitation of auditory neurons through coordinated acoustic and midbrain stimulation: investigating a deep brain stimulator for tinnitus.Journal of neural engineering · 2014Article
- Musicians' enhanced neural differentiation of speech sounds arises early in life: developmental evidence from ages 3 to 30.Cerebral cortex (New York, N.Y. : 1991) · 2014Article
- Reward contexts extend dopamine signals to unrewarded stimuli.Current biology : CB · 2014Article
- Histaminergic modulation of nonspecific plasticity of the auditory system and differential gating.Journal of neurophysiology · 2013Article
- Modulation of thalamic auditory neurons by the primary auditory cortex.Journal of neurophysiology · 2012Article
- Tuning shifts of the auditory system by corticocortical and corticofugal projections and conditioning.Neuroscience and biobehavioral reviews · 2012Review
- From behavioral context to receptors: serotonergic modulatory pathways in the IC.Frontiers in neural circuits · 2012Article
- Playing Music for a Smarter Ear: Cognitive, Perceptual and Neurobiological Evidence.Music perception · 2011Article
- Cholinergic cells of the pontomesencephalic tegmentum: connections with auditory structures from cochlear nucleus to cortex.Hearing research · 2011Review
- M1 muscarinic receptor for the development of auditory cortical function.Molecular brain · 2010Review
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2 authors at 1 institution in 1 country.
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Abstract
Experience-dependent plasticity in the central sensory systems depends on activation of both the sensory and neuromodulatory systems. Sensitization or nonspecific augmentation of central auditory neurons elicited by pseudo-conditioning with unpaired conditioning tonal (CS) and unconditioned electric leg (US) stimuli is quite different from tone-specific plasticity, called best frequency (BF) shifts, of the neurons elicited by auditory fear conditioning with paired CS and US. Therefore the neural circuits eliciting the nonspecific augmentation must be different from that eliciting the BF shifts. We first examined plastic changes in the response properties of collicular neurons of the big brown bat elicited by pseudo-conditioning and found that it elicited prominent nonspecific augmentation-an auditory response increase, a frequency-tuning broadening, and a threshold decreas-and that, in addition, it elicited a small short-lasting BF shift only when the CS frequency was 5 kHz lower than the BF of a recorded neuron. We examined the role of acetylcholine and the auditory and somatosensory cortices in these collicular changes. The development of the nonspecific augmentation was affected little by a muscarinic acetylcholine receptor antagonist applied to the inferior colliculus and by a GABA(A) receptor agonist applied to the auditory or somatosensory cortex. However, these drugs abolished the small short-lasting BF shift as they abolished the large long-lasting cortical and short-lasting collicular BF shifts elicited by the conditioning. These results indicate that, different from the BF shift, the nonspecific augmentation of the inferior colliculus depends on neither the cholinergic neuromodulator nor the auditory and somatosensory cortices.
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