ArticleEnvironmental research2009
Association of pediatric asthma severity with exposure to common household dust allergens.
Article in Environmental research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
46 citing papers in PubMed, 90 citations in OpenAlex.
- Cat exposure and asthma outcomes in a cohort of children with asthma and allergy.Frontiers in allergy · 2026Article
- Pet Ownership Increases the Exhaled Nitric Oxide and Asthma Severity in Children With Atopic Asthma.Allergy, asthma & immunology research · 2025Article
- The Impact of the Indoor Environment on Childhood Asthma.Current allergy and asthma reports · 2025Review
- Prognostic Factors in Severe Eosinophilic Asthma in a Pediatric Population: A Prospective Cohort Study in Spain.Journal of clinical medicine · 2024Article
- Sex and age characteristics of thunderstorm asthma emergency department visits.Hygiene and environmental health advances · 2024Article
- Ragweed Major Allergen Amb a 11 Recombinant Production and Clinical Implications.Biomolecules · 2023Article
- Environmental allergen reduction in asthma management: an overview.Frontiers in allergy · 2023Review
- Sensitization to molecular dog allergens in an adult population: Results from the West Sweden Asthma Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2023Article
- Thunderstorms, Pollen, and Severe Asthma in a Midwestern, USA, Urban Environment, 2007-2018.Epidemiology (Cambridge, Mass.) · 2022Article
- Inner-City Asthma in Children.Clinical reviews in allergy & immunology · 2019Review
- Severe Asthma and Allergy: A Pediatric Perspective.Frontiers in pediatrics · 2019Review
- Common allergies in urban adolescents and their relationships with asthma control and healthcare utilization.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018Article
- A model to predict the incidence of allergic rhinitis based on meteorological factors.Scientific reports · 2017Article
- Household biomass fuel use, asthma symptoms severity, and asthma underdiagnosis in rural schoolchildren in Nigeria: a cross-sectional observational study.BMC pulmonary medicine · 2017Observational
- Innate function of house dust mite allergens: robust enzymatic degradation of extracellular matrix at elevated pH.The World Allergy Organization journal · 2017Article
- Environmental triggers and avoidance in the management of asthma.Journal of asthma and allergy · 2017Review
- Association of Single Nucleotide Polymorphisms in the MD-2 Gene Promoter Region With Der p 2 Allergy.Allergy, asthma & immunology research · 2015Article
- Early childhood wheezers: identifying asthma in later life.Journal of asthma and allergy · 2015Review
- Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine.Environmental health perspectives · 2015Review
- Associations of neighborhood concentrated poverty, neighborhood racial/ethnic composition, and indoor allergen exposures: a cross-sectional analysis of los angeles households, 2006-2008.Journal of urban health : bulletin of the New York Academy of Medicine · 2014Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundReducing exposure to household dust inhalant allergens has been proposed as one strategy to reduce asthma.
objectiveTo examine the dose-response relationships and health impact of five common household dust allergens on disease severity, quantified using both symptom frequency and medication use, in atopic and non-atopic asthmatic children.
methodsAsthmatic children (N=300) aged 4-12 years were followed for 1 year. Household dust samples from two indoor locations were analyzed for allergens including dust mite (Der p 1, Der f 1), cat (Fel d 1), dog (Can f 1), cockroach (Bla g 1). Daily symptoms and medication use were collected in monthly telephone interviews. Annual disease severity was examined in models including allergens, specific IgE sensitivity and adjusted for age, gender, atopy, ethnicity, and mother's education.
resultsDer p 1 house dust mite allergen concentration of 2.0 microg/g or more from the main room and the child's bed was related to increased asthma severity independent of allergic status (respectively, OR 2.93, 95% CI 1.37, 6.30 for 2.0-10.0 microg/g and OR 2.55 95% CI 1.13, 5.73 for 10.0 microg/g). Higher pet allergen levels were associated with greater asthma severity, but only for those sensitized (cat OR 2.41 95% CI 1.19, 4.89; dog OR 2.06 95% CI 1.01, 4.22).
conclusionHigher levels of Der p 1 and pet allergens were associated with asthma severity, but Der p 1 remained an independent risk factor after accounting for pet allergens and regardless of Der p 1 specific IgE status.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.