ReviewThe European journal of neuroscience2009
Sleep function: current questions and new approaches.
Review in The European journal of neuroscience, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Impaired insulin signaling in human adipocytes after experimental sleep restriction: a randomized, crossover study.Annals of internal medicine · 2012Trial
- Sleep prevents brain phosphoproteome disruption to safeguard survival.Cell discovery · 2025Article
- Assessment of Dietary and Lifestyle Quality among the Romanian Population in the Post-Pandemic Period.Healthcare (Basel, Switzerland) · 2024Article
- Automated Observations of Dogs' Resting Behaviour Patterns Using Artificial Intelligence and Their Similarity to Behavioural Observations.Animals : an open access journal from MDPI · 2024Article
- Exploring the Mediating Role of Sleep Deficit-Related Functional Status in Subacute Stroke Survivors.Medicina (Kaunas, Lithuania) · 2024Article
- Effects of global postural re-education on stress and sleep quality in health sciences female students: a randomized controlled trial pilot study.Frontiers in psychiatry · 2024Article
- Article
- Neuropsychiatric symptoms and altered sleep quality in cerebral small vessel disease.Frontiers in psychiatry · 2022Article
- Perception of memory in university students of Venezuela during COVID-19Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2021Article
- Circadian Chimeric Mice Reveal an Interplay Between the Suprachiasmatic Nucleus and Local Brain Clocks in the Control of Sleep and Memory.Frontiers in neuroscience · 2021Article
- Sleep, Cognition and Cortisol in Addison's Disease: A Mechanistic Relationship.Frontiers in endocrinology · 2021Review
- Theta Oscillations Alternate With High Amplitude Neocortical Population Within Synchronized States.Frontiers in neuroscience · 2019Article
- Article
- Hypocretin (orexin) is critical in sustaining theta/gamma-rich waking behaviors that drive sleep need.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Dorsal vs. ventral differences in fast Up-state-associated oscillations in the medial prefrontal cortex of the urethane-anesthetized rat.Journal of neurophysiology · 2017Article
- Sleep, recovery, and metaregulation: explaining the benefits of sleep.Nature and science of sleep · 2015Article
- The evolutionary origin of the need to sleep: an inevitable consequence of synaptic neurotransmission?Frontiers in synaptic neuroscience · 2015Article
- Sleep smart-optimizing sleep for declarative learning and memory.Frontiers in psychology · 2015Review
- Baclofen facilitates sleep, neuroplasticity, and recovery after stroke in rats.Annals of clinical and translational neurology · 2014Article
- Cortical-subcortical interactions in hypersomnia disorders: mechanisms underlying cognitive and behavioral aspects of the sleep-wake cycle.Frontiers in neurology · 2014Review
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Authors and funding
2 authors.
Funding
Abstract
The mammalian brain oscillates through three distinct global activity states: wakefulness, non-rapid eye movement (NREM) sleep and REM sleep. The regulation and function of these 'vigilance' or 'behavioural' states can be investigated over a broad range of temporal and spatial scales and at different levels of functional organization, i.e. from gene expression to memory, in single neurons, cortical columns or the whole brain and organism. We summarize some basic questions that have arisen from recent approaches in the quest for the functions of sleep. Whereas traditionally sleep was viewed to be regulated through top-down control mechanisms, recent approaches have emphasized that sleep is emerging locally and regulated in a use-dependent (homeostatic) manner. Traditional markers of sleep homeostasis, such as the electroencephalogram slow-wave activity, have been linked to changes in connectivity and plasticity in local neuronal networks. Thus waking experience-induced local network changes may be sensed by the sleep homeostatic process and used to mediate sleep-dependent events, benefiting network stabilization and memory consolidation. Although many questions remain unanswered, the available data suggest that sleep function will best be understood by an analysis which integrates sleep's many functional levels with its local homeostatic regulation.
Indexed as
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19473236What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.