ArticleOrganic letters2009
Accessing skeletal diversity using catalyst control: formation of n and n + 1 macrocyclic triazole rings.
Article in Organic letters, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Green and Sustainable Chemistry Approaches on Azide-Based Click Reactions in Polymer Science.Macromolecular rapid communications · 2025Review
- Article
- Recent Progress on Synthesis of Functionalized 1,5-Disubstituted Triazoles.Current organic synthesis · 2024Review
- Insights on the Synthesis of N-Heterocycles Containing Macrocycles and Their Complexion and Biological Properties.Molecules (Basel, Switzerland) · 2022Review
- Synthetic and computational efforts towards the development of peptidomimetics and small-molecule SARS-CoV 3CLpro inhibitors.Bioorganic & medicinal chemistry · 2021Review
- Synthetic Strategy and Anti-Tumor Activities of Macrocyclic Scaffolds Based on 4-Hydroxyproline.Molecules (Basel, Switzerland) · 2016Article
- A diversity-oriented synthesis strategy enabling the combinatorial-type variation of macrocyclic peptidomimetic scaffolds.Organic & biomolecular chemistry · 2015Article
- A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling.Nature chemistry · 2013Article
- Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.Bioorganic & medicinal chemistry letters · 2013Article
- Skeletal diversification via heteroatom linkage control: preparation of bicyclic and spirocyclic scaffolds from N-substituted homopropargyl alcohols.The Journal of organic chemistry · 2013Article
- Preparation of 1,5-Disubstituted 1,2,3-Triazoles via Ruthenium-catalyzed Azide Alkyne Cycloaddition.Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals · 2013Article
- Build/couple/pair strategy for the synthesis of stereochemically diverse macrolactams via head-to-tail cyclization.ACS combinatorial science · 2012Article
- Diversity-oriented synthesis of macrocyclic peptidomimetics.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Journal of the American Chemical Society · 2010Article
- Automated synthesis of a 96 product-sized library of triazole derivatives using a solid phase supported copper catalyst.Molecules (Basel, Switzerland) · 2010Article
- Regioselective intramolecular dipolar cycloaddition of azides and unsymmetrical alkynes.Organic letters · 2010Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A regioselective intramolecular Huisgen cycloaddition was performed on various azido alkyne substrates giving rise to macrocyclic triazole rings. Using catalyst control, a common intermediate has been converted to two structurally unique macrocycles with either a 1,5- or a 1,4-triazole resulting in an n or n + 1 ring size. This is the first example of an intramolecular ruthenium-catalyzed Huisgen cycloaddition.
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