ArticleJournal of magnetic resonance imaging : JMRI2009
Relaxation times of skeletal muscle metabolites at 7T.
Article in Journal of magnetic resonance imaging : JMRI, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 42 citations in OpenAlex.
- Ultrasound predicts skeletal muscle fat infiltration in healthy middle-aged and young adults: Validation against MRI.Experimental physiology · 2026Trial
- Quantification of cross-relaxation in downfieldMagnetic resonance in medicine · 2023Article
- Water-suppression cycling 3-T cardiacNMR in biomedicine · 2021Article
- Comparison of single-voxelJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021Article
- Musculoskeletal MRI at 7 T: do we need more or is it more than enough?European radiology experimental · 2020Review
- Review
- In vivo high-resolution magic angle spinning magnetic and electron paramagnetic resonance spectroscopic analysis of mitochondria-targeted peptide in Drosophila melanogaster with trauma-induced thoracic injury.International journal of molecular medicine · 2016Article
- Fiber orientation measurements by diffusion tensor imaging improve hydrogen-1 magnetic resonance spectroscopy of intramyocellular lipids in human leg muscles.Journal of medical imaging (Bellingham, Wash.) · 2015Article
- Evaluation of subchondral bone marrow lipids of acute anterior cruciate ligament (ACL)-injured patients at 3 T.Academic radiology · 2014Article
- MRI of the hip at 7T: feasibility of bone microarchitecture, high-resolution cartilage, and clinical imaging.Journal of magnetic resonance imaging : JMRI · 2014Article
- The role of interleukin 17 in tumour proliferation, angiogenesis, and metastasis.Mediators of inflammation · 2014Review
- Noninvasive monitoring of training induced muscle adaptation with 31P-MRS: fibre type shifts correlate with metabolic changes.BioMed research international · 2013Article
- MRI/MRS evaluation of a female carrier of Duchenne muscular dystrophy.Neuromuscular disorders : NMD · 2012Article
- Assessment of subchondral bone marrow lipids in healthy controls and mild osteoarthritis patients at 3T.NMR in biomedicine · 2012Article
- 1H-MRS of hepatic fat using short TR at 3T: SNR optimization and fast T2 relaxometry.Magma (New York, N.Y.) · 2011Article
- T₁-corrected fat quantification using chemical shift-based water/fat separation: application to skeletal muscle.Magnetic resonance in medicine · 2011Article
- Removal of olefinic fat chemical shift artifact in diffusion MRI.Magnetic resonance in medicine · 2011Article
- In vivo high-resolution magic angle spinning magnetic resonance spectroscopy of Drosophila melanogaster at 14.1 T shows trauma in aging and in innate immune-deficiency is linked to reduced insulin signaling.International journal of molecular medicine · 2010Article
- Biochemical and physiological MR imaging of skeletal muscle at 7 tesla and above.Seminars in musculoskeletal radiology · 2010Review
- In vivo 1D and 2D correlation MR spectroscopy of the soleus muscle at 7T.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo demonstrate the feasibility of quantitatively evaluating and measuring T(1) and T(2) relaxation times of human tibialis anterior (TA) muscles metabolites in vivo at 7T and to compare these results with those of 3T. MATERIALS AND
methodsA model lipid phantom (corn oil) and healthy volunteers (n = 4, mean +/- SD age 35.6 +/- 5.6 years) were scanned on 3T and 7T whole-body MR scanners. A voxel of 10 x 10 x 10 mm(3) was positioned on the lipid phantom and right calf TA muscles using the single-voxel stimulated echo acquisition mode (STEAM) pulse sequence. All magnetic resonance spectroscopy (MRS) data were processed with Java-based Magnetic Resonance User Interface (JMRUI) using Hankel Lanczos Singular Value Decomposition (HLSVD) filtering to remove the residual water signal.
resultsT(1) shows a steady increase while T(2) shows a slight decrease with B(0) and the spectra show larger spectral resolution at 7T than at 3T in the lipid phantom. T(1) values of all the metabolites are higher, while T(2) values are slightly lower at 7T than those of 3T compared to reported results in TA. The maximum percentage of increase in T(1) is about approximately 488%, the maximum percentage of decrease in T(2) is about approximately 65%.
conclusionThe preliminary results can potentially be used for calculating relaxation correction factors required for absolute quantitation of skeletal muscle metabolite concentrations and for further protocol and sequence optimization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.