ArticleWorld journal of gastroenterology2009
Risk factors for sporadic colorectal cancer in southern Chinese.
Article in World journal of gastroenterology, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Risk Prediction Models for Colorectal Cancer: A Systematic Review.Cancer prevention research (Philadelphia, Pa.) · 2016Pooled it
- Association between alcohol consumption and cancers in the Chinese population--a systematic review and meta-analysis.PloS one · 2011Pooled it
- Colorectal Cancer Risk Awareness and Screening Uptake among Adults in the United Arab EmiratesAsian Pacific journal of cancer prevention : APJCP · 2018Article
- External validation of risk prediction models for incident colorectal cancer using UK Biobank.British journal of cancer · 2018Article
- Rectal Cancer in Asian vs. Western Countries: Why the Variation in Incidence?Current treatment options in oncology · 2017Review
- Cancer prevention and control: alarming challenges in China.National science review · 2016Article
- Decreased expression of dual specificity phosphatase 22 in colorectal cancer and its potential prognostic relevance for stage IV CRC patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- Polymorphisms in arachidonic acid metabolism-related genes and the risk and prognosis of colorectal cancer.Familial cancer · 2013Article
- Diabetes but not insulin is associated with higher colon cancer mortality.World journal of gastroenterology · 2012Article
- Colorectal cancer screening: comparison of transferrin and immuno fecal occult blood test.World journal of gastroenterology · 2012Article
- Association of the colorectal cancer and MDR1 gene polymorphism in an Iranian population.Molecular biology reports · 2011Article
- Colorectal cancer in Guangdong Province of China: a demographic and anatomic survey.World journal of gastroenterology · 2010Article
- Risk factors for colon cancer in Northeastern Thailand: interaction of MTHFR codon 677 and 1298 genotypes with environmental factors.Journal of epidemiology · 2010Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the role of smoking, alcohol drinking, family history of cancer, and body mass index (BMI) in sporadic colorectal cancer in southern Chinese.
methodsA hospital-based case-control study was conducted from July 2002 to December 2008. There were 706 cases and 723 controls with their sex and age (within 5 years) matched. An unconditional logistic regression model was used to analyze the association between smoking, alcohol drinking, family history of cancer, BMI and sporadic colorectal cancer.
resultsNo positive association was observed between smoking status and sporadic colorectal cancer risk. Compared with the non alcohol drinkers, the current and former alcohol drinkers had an increased risk of developing sporadic colorectal cancer (CRC) (adjusted OR = 8.61 and 95% CI = 6.15-12.05; adjusted OR = 2.30, 95% CI = 1.27-4.17). Moreover, the increased risk of developing sporadic CRC was significant in those with a positive family history of cancer (adjusted OR = 1.62, 95% CI = 1.12-3.34) and in those with their BMI >or= 24.0 kg/m(2) (adjusted OR = 1.39, 95% CI = 1.10-1.75). Stratification analysis showed that the risk of developing both colon and rectal cancers was increased in current alcohol drinkers (adjusted OR = 7.60 and 95% CI = 5.13-11.25; adjusted OR = 7.52 and 95% CI = 5.13-11.01) and in those with their BMI >or= 24.0 kg/m(2) (adjusted OR = 1.38 and 95% CI = 1.04-1.83; adjusted OR = 1.35 and 95% CI = 1.02-1.79). The risk of developing colon cancer, but not rectal cancer, was found in former alcohol drinkers and in those with a positive family history of cancer (adjusted OR = 2.51 and 95% CI = 1.24-5.07; adjusted OR = 1.82 and 95% CI = 1.17-2.82).
conclusionAlcohol drinking, high BMI (>or= 24.0 kg/m(2)) and positive family history of cancer are the independent risk factors for colorectal cancer in southern Chinese.
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