ArticleParasitology research2009
Comparative in vitro effect of artemether and albendazole on adult Toxocara canis.
Article in Parasitology research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 29 citations in OpenAlex.
- In vitro Evaluation of the Nematicidal Efficacy of Quercetin on Adult Toxocara canis.Acta parasitologica · 2025Article
- Article
- Two-photon NAD(P)H-FLIM reveals unperturbed energy metabolism of Ascaris suum larvae, in contrast to host macrophages upon artemisinin derivatives exposure.Scientific reports · 2025Article
- Discovery of Novel Thiazolohydrazone Derivatives as an Alternative Option in the Treatment of Zoonotic Toxocara canis: In Vitro and In Silico Evaluation.Veterinary medicine and science · 2025Article
- Efficacy of artemether against toxocariasis in mice: parasitological and immunopathological changes in brain, liver, and lung.Pathogens and global health · 2024Article
- In vitro anti-Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Microscopic Study of Mechanoreceptors and Chemoreceptors of Anterior and Posterior Ends of Toxocara Canis Using Scanning Electron Microscopy and Light Microscope.Archives of Razi Institute · 2021Article
- Review
- Toxocara canis Mimicking a Metastatic Omental Mass from Sigmoid Colon Cancer: A Case Report.Annals of coloproctology · 2018Article
- Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq.International journal for parasitology. Drugs and drug resistance · 2016Article
- Larvicidal activity of camphor and lavender oils against sheep blowfly,Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
- Combined subacute toxicity of copper and antiparasitic albendazole to the earthworm (Eisenia fetida).Environmental science and pollution research international · 2016Article
- Ultrastructural changes in the advanced third larval stage of Gnathostoma binucleatum Almeyda-Artigas, 1991 (Nematoda: Spirurida) following albendazole and albendazole sulfoxide in vitro exposure.Parasitology research · 2012Article
- In Vitro Assessment ofIranian journal of parasitologyArticle
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the integrity of Toxocara canis cuticle is essential for the nutritive and protective functions, light and scanning electron microscopic studies were undertaken to assess, for the first time, whether artemether had any effect on the cuticle including lips and sensory organs following 24 and 48 h incubation in vitro. The results were compared with those observed in the worm cuticle following incubation in albendazole, as it was 100% effective against adult nematode. The body cover changes seen after in vitro administration of artemether were similar to that induced by albendazole sulfoxide, active form, (ABZ-SO). However, the earlier onset of those changes was recorded with the former. The swollen appearance of the anterior end of T. canis, including the lips, distortion of some sensory papillae, and appearance of a number of lesions on the lips, were observed during in vitro action of artemether. Cuticular disruption had also been observed in adult T canis exposed to ABZ-SO. The surface changes were more severe than those observed following incubation in artemether, with which limited loss of the cuticle occurred in the lips of nematode but was not as widespread as that seen with ABZ-SO. However, the cuticular swelling of the anterior end of T canis was more pronounced than that with ABZ-SO. In the present study, artemether presented itself as a drug that might become important in nematode chemotherapy, besides its broad spectrum of activity against various trematodes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.