ReviewInternational journal of molecular sciences2009
Pseudo-replication of [GADV]-proteins and origin of life.
Review in International journal of molecular sciences, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- The Evolution of the First Code.Genes · 2026Review
- Role of metal(ii) hexacyanocobaltate(iii) surface chemistry for prebiotic peptides synthesis.RSC advances · 2025Article
- Chemical Evolution of Life on Earth.Genes · 2025Review
- The 3 31 Nucleotide Minihelix tRNA Evolution Theorem and the Origin of Life.Life (Basel, Switzerland) · 2023Review
- A crescendo of competent coding (c3) contains the Standard Genetic Code.RNA (New York, N.Y.) · 2022Article
- How Did Life Emerge in Chemically Complex Messy Environments?Life (Basel, Switzerland) · 2022Article
- Prebiotic Peptides Based on the Glycocodon Theory Analyzed with FRET.Life (Basel, Switzerland) · 2021Article
- Evolution of the genetic code.Transcription · 2021Review
- Theoretical Analysis of S, M and N Structural Proteins by the Protein-RNA Recognition Code Leads to Genes/proteins that Are Relevant to the SARS-CoV-2 Life Cycle and Pathogenesis.Frontiers in genetics · 2021Article
- The Origin of tRNA Deduced from Pseudomonas aeruginosa 5' Anticodon-Stem Sequence : Anticodon-stem loop hypothesis.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2019Article
- A Proposal of the Ur-proteome.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2018Article
- Formation of Diastereoisomeric Piperazine-2,5-dione from DL-Alanine in the Presence of Olivine and Water.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017Article
- Evolutionary Steps in the Emergence of Life Deduced from the Bottom-Up Approach and GADV Hypothesis (Top-Down Approach).Life (Basel, Switzerland) · 2016Review
- Predicting three-dimensional conformations of peptides constructed of only glycine, alanine, aspartic acid, and valine.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2015Article
- Protein ordered sequences are formed by random joining of amino acids in protein 0(th)-order structure, followed by evolutionary process.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2014Article
- [GADV]-protein world hypothesis on the origin of life.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2014Article
- Uniquely localized intra-molecular amino acid concentrations at the glycolytic enzyme catalytic/active centers of Archaea, Bacteria and Eukaryota are associated with their proposed temporal appearances on earth.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2013Article
- Abiotic formation of valine peptides under conditions of high temperature and high pressure.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2012Article
- Proteome evolution and the metabolic origins of translation and cellular life.Journal of molecular evolution · 2011Article
- Editorial: hypotheses about protein folding--the proteomic code and wonderfolds.Theoretical biology & medical modelling · 2009Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The RNA world hypothesis on the origin of life is generally considered as the key to solve the "chicken and egg dilemma" concerning the evolution of genes and proteins as observed in the modern organisms. This hypothesis, however, contains several serious weak points. We have a counterproposal called [GADV]-protein world hypothesis, abbreviated as GADV hypothesis, in which we have suggested that life originated from a [GADV]-protein world, which comprised proteins composed of four amino acids: Gly [G], Ala [A], Asp [D], and Val [V]. A new concept "pseudo-replication" is crucial for the description of the emergence of life. The new hypothesis not only plausibly explains how life originated from the initial chaotic protein world, but also how genes, genetic code, and proteins co-evolved.
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