Evidence map›Paper›PMID 19466671›Full record

ReviewJournal of toxicology and environmental health. Part B, Critical reviews2009

Human exposure to selected animal neurocarcinogens: a biomarker-based assessment and implications for brain tumor epidemiology.

Dora Il'yasova, Bridget J McCarthy, Serap Erdal, Joanna Shimek, Jennifer Goldstein, Daniel R Doerge, Steven R Myers, Paolo Vineis, John S Wishnok, James A Swenberg and 2 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of toxicology and environmental health. Part B, Critical reviews, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 2 countries.

Dora Il'yasovaPreston Robert Tisch Brain Tumor Center at Duke and Department of Community and Family Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA. dora.ilyasova@duke.edu
Bridget J McCarthy
Serap Erdal
Joanna Shimek
Jennifer Goldstein
Daniel R Doerge
Steven R Myers
Paolo Vineis
John S Wishnok
James A Swenberg
Darell D Bigner
Faith G Davis
University of Illinois Chicago · USDuke Medical Center · USImperial College London · GBMassachusetts Institute of Technology · USPediatric Brain Tumor Foundation · USUnited States Food and Drug Administration · USUniversity of Louisville Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

TUMOR SUPPRESSOR GENES IN HUMAN MEDULLOBLASTOMAP50NS020023 · NINDS · DUKE UNIVERSITY · PI BIGNER, DARELL D · 1985 to 2013
$17.3M
TEMODAR RESISTANCE IN CENTRAL NERVOUS SYSTEMP50CA108786 · NCI · DUKE UNIVERSITY · PI BIGNER, DARELL D · 2004 to 2009
$12.3M
BRAIN TUMORS: IMMUNOLOGICAL AND BIOLOGICAL STUDIESR37CA011898 · NCI · DUKE UNIVERSITY · PI BIGNER, DARELL D · 1988 to 2012
$8.1M
NCI NIH HHS 5P50 CA108786-4NCI NIH HHS P50 CA108786NCI NIH HHS R37 CA011898NCI NIH HHS R37 CA011898-38NINDS NIH HHS 5P50 NS20023-25NINDS NIH HHS P50 NS020023
6 · The paper itself

Abstract

This review is based on the proceedings from the Second Lebow Conference, held in Chicago in 2007. The conference concentrated on developing a framework for innovative studies in the epidemiology of environmental exposures, focusing specifically on the potential relationship with brain tumors. Researchers with different perspectives, including toxicology, pharmacokinetics, and epidemiological exposure assessment, exchanged information and ideas on the use of biomarkers of exposure in molecular epidemiology studies and summarized the current knowledge on methods and approaches for biomarker-based exposure assessment. This report presents the state of science regarding biomarker-based exposure assessment of the four most common neurocarcinogens: acrylamide, 1,3-butadiene, N-nitroso compounds, and polycyclic aromatic hydrocarbons. Importantly, these chemicals are also carcinogenic in other organs; therefore, this discussion is useful for environmental epidemiologists studying all cancer types.

Indexed as

AcrylamideAnimalsAnimals, LaboratoryBiomarkers, TumorBrain NeoplasmsButadienesCarcinogens, EnvironmentalEnvironmental ExposureEnvironmental MonitoringEpidemiological MonitoringHumansMolecular EpidemiologyNitroso CompoundsPolycyclic Aromatic HydrocarbonsRisk Assessment1,3-butadieneAcrylamideBiomarkers, TumorButadienesCarcinogens, EnvironmentalNitroso CompoundsPolycyclic Aromatic Hydrocarbons

Identifiers

PMID19466671
PMCPMC3633093
OpenAlexW1990365979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.