ArticleMolecular biology reports2010
Different messenger RNA expression for the antimicrobial peptides beta-defensins between Meishan and crossbred pigs.
Article in Molecular biology reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 27 citations in OpenAlex.
- NF-κB/AP-1-mediated expression of the porcine cathelicidin proPMAP-37 suppresses inflammation by neutralizing LPS and inhibiting M1 macrophage polarization.BMC veterinary research · 2026Article
- Genome-wide analysis of circRNA regulation during spleen development of Chinese indigenous breed Meishan pigs.BMC genomics · 2023Article
- Effect of Supplementation with Organic Selenium or Turmeric and Rosemary Mixture on Beta-Defensin Content in Goat Milk.Animals : an open access journal from MDPI · 2022Article
- Integrated analysis of lncRNA-mediated ceRNA network involved in immune regulation in the spleen of Meishan piglets.Frontiers in veterinary science · 2022Article
- Generation of Marker-FreeGenes · 2020Article
- Porcine β-defensin 2 inhibits proliferation of pseudorabies virus in vitro and in transgenic mice.Virology journal · 2020Article
- Expression and Functional Characterization of a Novel Antimicrobial Peptide: Human Beta-Defensin 118.BioMed research international · 2020Article
- β-Defensin 129 Attenuates Bacterial Endotoxin-Induced Inflammation and Intestinal Epithelial Cell Apoptosis.Frontiers in immunology · 2019Article
- Differential expression, molecular cloning, and characterization of porcine beta defensin 114.Journal of animal science and biotechnology · 2019Article
- Genome-wide genetic variation discovery in Chinese Taihu pig breeds using next generation sequencing.Animal genetics · 2017Article
- Overexpression of Porcine Beta-Defensin 2 Enhances Resistance to Actinobacillus pleuropneumoniae Infection in Pigs.Infection and immunity · 2015Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
beta-Defensins are cysteine-rich endogenously produced antimicrobial peptides that play an important role in innate immunity. In this study, the expressions of genes porcine beta-defensins-1(pBD-1), pBD-2 and pBD-3 were determined using real-time PCR for Chinese Meishan pigs and Crossbred (Duroc x Yorkshire x Landrace) pigs of 7 days old in various tissues. The results showed that expressions of pBD-1, 2 and 3 of Meishan pigs in most tissues were higher than those of crossbred pigs and main expression sites for pBD-1 and pBD-3 were tongue and oral mucosa in two varieties of pigs, whereas pBD-2 of crossbred pig was mainly expressed in kidney and liver, and pBD-2 of Meishan pigs mainly in tongue and oral mucosa. The higher expression of pBDs might be the reason of Meishan pigs has higher immunity and disease resistance. The mechanisms of this need a further research.
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