Evidence map›Paper›PMID 19466551›Full record

ReviewApoptosis : an international journal on programmed cell death2009

By design or by chance: cell death during Drosophila embryogenesis.

Nianwei Lin, Can Zhang, John Pang, Lei Zhou

Abstract readReview
In one paragraph

Review in Apoptosis : an international journal on programmed cell death, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nianwei LinDepartment of Molecular Genetics and Microbiology, UF Shands Cancer Center, University of Florida, Gainesville, FL 32610-0232, USA.
Can Zhang
John Pang
Lei Zhou

Funding

Probing Complexity of UV Induced Apoptosis in DrosophilaR01CA095542 · NCI · UNIVERSITY OF FLORIDA · PI ZHOU, LEI · 2003 to 2007
$1.2M
Comparative Analysis of Cell Death Regulation in MosquitoesR21AI067555 · NIAID · UNIVERSITY OF FLORIDA · PI ZHOU, LEI · 2006 to 2007
$394k
NCI NIH HHS CA095542NCI NIH HHS R01 CA095542NIAID NIH HHS AI067555NIAID NIH HHS R21 AI067555
6 · The paper itself

Abstract

Cell death plays an essential role during Drosophila embryogenesis. However, it remains an enigma as to what mechanisms determine (or select) the specific cells to be eliminated at a particular developmental stage. Is it mostly dependent on the lineage of the cell, signifying genetic predetermination, or is it due to the failure of a cell to compete for growth factors, which is more or less by chance? Recent developments in studying the molecular mechanism of cell death during Drosophila embryogenesis has provided much insight into our understanding of the relative importance of, and the interaction between, these two mechanisms in shaping the embryo.

Indexed as

AnimalsCell DeathDrosophilaDrosophila ProteinsEmbryo, NonmammalianGenome, InsectInhibitor of Apoptosis ProteinsIntercellular Signaling Peptides and ProteinsDrosophila ProteinsInhibitor of Apoptosis ProteinsIntercellular Signaling Peptides and Proteins

Identifiers

PMID19466551
PMCPMC2901921

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.