Evidence map›Paper›PMID 19465829›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2009

CCR2-64I polymorphism is associated with lower maternal HIV-1 viral load and reduced vertical HIV-1 transmission.

Jennifer M Mabuka, Romel D Mackelprang, Barbara Lohman-Payne, Maxwell Majiwa, Rose Bosire, Grace John-Stewart, Sarah Rowland-Jones, Julie Overbaugh, Carey Farquhar

Abstract readLetter
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. The application of clinical genetics · 2019
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jennifer M Mabuka
Romel D Mackelprang
Barbara Lohman-Payne
Maxwell Majiwa
Rose Bosire
Grace John-Stewart
Sarah Rowland-Jones
Julie Overbaugh
Carey Farquhar

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Kenneth Sherr · 1988 to 2026
$104.9M
INTERNATIONAL TRAINING GRANT IN EPIDEMIOLOGYD43TW000007 · FIC · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 1988 to 2012
$16.3M
Urgent Versus Post-Stabilization ART in HIV+ Children with Severe Co-infectionsR01HD023412 · NICHD · UNIVERSITY OF WASHINGTON · PI Grace C. John-Stewart, DALTON CHEKOKO WAMALWA · 1987 to 2026
$12.2M
CCR5 and CXCR4 Binding Chemokines and Oral HIV InfectionR01DE014826 · NIDCR · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C · 2002 to 2005
$1.2M
Protective Immune Responses in HIV-1 Exposed InfantsK23HD041879 · NICHD · UNIVERSITY OF WASHINGTON · PI FARQUHAR, CAREY · 2002 to 2006
$628k
CTL responses in HIV-1 infected infantsK01TW006080 · FIC · UNIVERSITY OF WASHINGTON · PI PAYNE, BARBARA LOUISE · 2002 to 2005
$495k
FIC NIH HHS D43 TW000007FIC NIH HHS K01 TW006080Medical Research Council MC_U137884180NIAID NIH HHS P30 AI027757NICHD NIH HHS HD23412NICHD NIH HHS HD41879NICHD NIH HHS K23 HD041879NICHD NIH HHS R01 HD023412NIDCR NIH HHS DE14826NIDCR NIH HHS R01 DE014826
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Infectious Disease Transmission, VerticalPolymorphism, GeneticViral LoadAdultAnti-HIV AgentsCD4 Lymphocyte CountCohort StudiesFemaleGenetic Predisposition to DiseaseHIV InfectionsHumansInfant, NewbornKenyaPregnancyReceptors, CCR2ZidovudineAnti-HIV AgentsCCR2 protein, humanReceptors, CCR2Zidovudine

Identifiers

PMID19465829
PMCPMC2732713

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.