Evidence map›Paper›PMID 19465049›Full record

ReviewPlasmid2009

Replication and conjugative mobilization of broad host-range IncQ plasmids.

Richard Meyer

Abstract readReview
In one paragraph

Review in Plasmid, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 96 papers.

0numbers the graph read from it
0cells of the map it votes in
96citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

96 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. The extended mobility of plasmids.Nucleic acids research · 2025
    Review
  10. Article
  11. Article
  12. Evaluation of vectors for gene expression inApplied and environmental microbiology · 2025
    Article
  13. Article
  14. Genotypic and phenotypic analyses of two distinct sets ofJournal of medical microbiology · 2025
    Article
  15. Article
  16. Article
  17. Delivery of functional Cas:DNA nucleoprotein complexes into recipient bacteria through a type IV secretion system.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
  19. Article
  20. Multidrug resistance in pathogenicFrontiers in veterinary science · 2024
    Article

36 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Richard MeyerInstitute for Cell and Molecular Biology, University of Texas at Austin, 78712-0162, USA. rmeyer@mail.utexas.edu

Funding

CONJUGATIVE MOBILIZATION OF PLASMID R1162R01GM037462 · NIGMS · UNIVERSITY OF TEXAS AUSTIN · PI MEYER, RICHARD J · 1987 to 2003
$997k
NIGMS NIH HHS R01 GM037462
6 · The paper itself

Abstract

The IncQ plasmids have a broader host-range than any other known replicating element in bacteria. Studies on the replication and conjugative mobilization of these plasmids, which have mostly been focused on the nearly identical RSF1010 and R1162, are summarized with a view to understanding how this broad host-range is achieved. Several significant features of IncQ plasmids emerge from these studies: (1) initiation of replication, involving DnaA-independent activation of the origin and a dedicated primase, is strictly host-independent. (2) The plasmids can be conjugatively mobilized by a variety of different type IV transporters, including those engaged in the secretion of proteins involved in pathogenesis. (3) Stability is insured by a combination of high copy-number and modulated gene expression to reduce metabolic load.

Indexed as

DNA ReplicationBacteriaConjugation, GeneticDNA, BacterialGene DosagePlasmidsDNA, Bacterial

Identifiers

PMID19465049
PMCPMC2752045

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.