ArticleVirus research2009
Molecular characterization of a new PToV strain. Evolutionary implications.
Article in Virus research, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 25 citations in OpenAlex.
- Cleavage of cellular substrate porcine gasdermin D by porcine torovirus 3C-like protease induces pyroptosis.Virulence · 2026Article
- Reverse Genetics with a Full-Length Infectious cDNA Clone of Bovine Torovirus.Journal of virology · 2022Article
- Recent Progress in Torovirus Molecular Biology.Viruses · 2021Review
- Characterization of Self-Processing Activities and Substrate Specificities of Porcine Torovirus 3C-Like Protease.Journal of virology · 2020Article
- Porcine Torovirus (PToV)-A Brief Review of Etiology, Diagnostic Assays and Current Epidemiology.Frontiers in veterinary science · 2019Review
- The use of convalescent sera in immune-electron microscopy to detect non-suspected/new viral agents.Viruses · 2015Article
- Genome sequence of torovirus identified from a pig with porcine epidemic diarrhea virus from the United States.Genome announcements · 2014Article
- Molecular characterization and phylogenetic analysis of the genome of porcine torovirus.Archives of virology · 2014Article
- Lineage specific antigenic differences in porcine torovirus hemagglutinin-esterase (PToV-HE) protein.Veterinary research · 2013Article
- Evolution and homologous recombination of the hemagglutinin-esterase gene sequences from porcine torovirus.Virus genes · 2013Article
- Molecular detection of porcine torovirus in piglets with diarrhea in southwest China.TheScientificWorldJournal · 2013Article
- Seroprevalence of porcine torovirus (PToV) in Spanish farms.BMC research notes · 2012Article
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- Longitudinal serological and virological study on porcine torovirus (PToV) in piglets from Spanish farms.Veterinary microbiology · 2010Article
- Development of universal SYBR Green real-time RT-PCR for the rapid detection and quantitation of bovine and porcine toroviruses.Journal of virological methods · 2010Article
- Detection and molecular characterization of porcine toroviruses in Korea.Archives of virology · 2010Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toroviruses are emergent viruses, belonging to the Nidovirales order, that remain mostly ignored, despite they are able to infect different species of domestic animals and humans, causing enteric diseases and diarrhea. Thus far, only five variants of porcine torovirus (PToV) have been identified. In this report we describe the identification and partial characterization of a new strain of porcine torovirus (PToV-BRES) that was detected by RT-PCR in a swine faecal specimen from a farm in Brescia (Italy). The complete genes coding for the nucleocapsid (N), hemagglutinin-esterase (HE) and membrane (M) proteins were amplified, and sequence analysis showed that PToV-BRES is a new PToV strain that, based on the HE gene sequence, is phylogenetically related to P4 strain, that was up to now the only member of a distinct PToV lineage. The nucleocapsid protein from PToV-BRES was expressed in insect cells as a his-tagged protein, purified by affinity chromatography and used to develop an ELISA method to detect antibodies against PToV. This assay was evaluated using a serum collection including 45 samples from three commercial farms from Spain. High antibody prevalence against PToV was observed in the three farms, both in adult animals and in piglets, which could suggest that PToV might be endemic in Spanish porcine population. The ELISA method developed in this work could be useful in future epidemiological surveys about toroviruses.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.